Detailed information NTG0294870

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSB81_RS04455
• Genome accession: NZ_CP029667
• Coordinates: 784694..785737 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AR_0225
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 779694..790737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB81_RS04410	-	780123..780233 (+)	111	WP_001790257.1	hypothetical protein	-
CSB81_RS04415 (CSB81_0763)	-	780262..780675 (+)	414	WP_001549145.1	hypothetical protein	-
CSB81_RS04425 (CSB81_0764)	-	781106..782092 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
CSB81_RS04440 (CSB81_0765)	map	782620..783378 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CSB81_RS04445 (CSB81_0766)	-	783595..783981 (+)	387	WP_001110179.1	hypothetical protein	-
CSB81_RS04450 (CSB81_0767)	liaF	783996..784697 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CSB81_RS04455 (CSB81_0768)	vraS	784694..785737 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CSB81_RS04460 (CSB81_0769)	vraR	785727..786356 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
CSB81_RS04465 (CSB81_0770)	-	786472..787689 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
CSB81_RS04470 (CSB81_0771)	-	787967..788242 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
CSB81_RS04475 (CSB81_0772)	-	788249..788713 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CSB81_RS04480 (CSB81_0773)	-	788860..789060 (+)	201	WP_000180461.1	DUF1128 family protein	-
CSB81_RS04485 (CSB81_0774)	-	789063..790319 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=294870 CSB81_RS04455 WP_001017131.1 784694..785737(+) (vraS) [Staphylococcus aureus strain AR_0225]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294870 CSB81_RS04455 WP_001017131.1 784694..785737(+) (vraS) [Staphylococcus aureus strain AR_0225]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1