Detailed information NTG0294734

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: CSC52_RS10855
• Genome accession: NZ_CP029658
• Coordinates: 2037313..2038299 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AR_0467
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 2032313..2043299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC52_RS10830 (CSC52_2038)	-	2032573..2032920 (-)	348	WP_001242103.1	hypothetical protein	-
CSC52_RS10835 (CSC52_2039)	-	2033106..2033699 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
CSC52_RS10840 (CSC52_2040)	-	2033803..2034168 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
CSC52_RS10845 (CSC52_2041)	yjbH	2034191..2034997 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
CSC52_RS10850 (CSC52_2042)	pepF	2035457..2037265 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
CSC52_RS10855 (CSC52_2043)	coiA	2037313..2038299 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
CSC52_RS10860 (CSC52_2044)	mecA	2038420..2039139 (-)	720	WP_001217728.1	adaptor protein MecA	-
CSC52_RS10865 (CSC52_2045)	spxA	2039510..2039905 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
CSC52_RS10870 (CSC52_2046)	trpS	2040199..2041188 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
CSC52_RS10875 (CSC52_2047)	opp4C	2041230..2042111 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
CSC52_RS10880 (CSC52_2048)	opp4B	2042123..2043085 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=294734 CSC52_RS10855 WP_000959282.1 2037313..2038299(-) (coiA) [Staphylococcus aureus strain AR_0467]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=294734 CSC52_RS10855 WP_000959282.1 2037313..2038299(-) (coiA) [Staphylococcus aureus strain AR_0467]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976