Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   CSC52_RS07310 Genome accession   NZ_CP029658
Coordinates   1339304..1339990 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain AR_0467     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1334304..1344990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC52_RS07275 (CSC52_1355) yqeH 1334831..1335931 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  CSC52_RS07280 (CSC52_1356) aroE 1335945..1336751 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  CSC52_RS07285 (CSC52_1357) yhbY 1336755..1337045 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  CSC52_RS07290 (CSC52_1358) nadD 1337048..1337617 (+) 570 Protein_1331 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  CSC52_RS07295 (CSC52_1359) yqeK 1337607..1338191 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CSC52_RS07300 (CSC52_1360) rsfS 1338192..1338545 (+) 354 WP_001088020.1 ribosome silencing factor -
  CSC52_RS07305 (CSC52_1361) - 1338548..1339264 (+) 717 WP_000084830.1 class I SAM-dependent methyltransferase -
  CSC52_RS07310 (CSC52_1362) comEA 1339304..1339990 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  CSC52_RS07315 (CSC52_1363) - 1340082..1340543 (+) 462 WP_000439693.1 ComE operon protein 2 -
  CSC52_RS07320 (CSC52_1364) comEC 1340548..1342749 (+) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CSC52_RS07325 (CSC52_1365) holA 1342806..1343780 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  CSC52_RS07330 (CSC52_1366) rpsT 1343825..1344076 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=294720 CSC52_RS07310 WP_001802022.1 1339304..1339990(+) (comEA) [Staphylococcus aureus strain AR_0467]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=294720 CSC52_RS07310 WP_001802022.1 1339304..1339990(+) (comEA) [Staphylococcus aureus strain AR_0467]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACCTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment