Detailed information NTG0294648

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: CSC54_RS12605
• Genome accession: NZ_CP029655
• Coordinates: 2410617..2411603 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AR_0469
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 2405617..2416603

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC54_RS12580 (CSC54_2275)	-	2405877..2406224 (-)	348	WP_001242103.1	hypothetical protein	-
CSC54_RS12585 (CSC54_2276)	-	2406410..2407003 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
CSC54_RS12590 (CSC54_2277)	-	2407107..2407472 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
CSC54_RS12595 (CSC54_2278)	yjbH	2407495..2408301 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
CSC54_RS12600 (CSC54_2279)	pepF	2408761..2410569 (-)	1809	WP_001655747.1	oligoendopeptidase F	-
CSC54_RS12605 (CSC54_2280)	coiA	2410617..2411603 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
CSC54_RS12610 (CSC54_2281)	mecA	2411724..2412443 (-)	720	WP_001217728.1	adaptor protein MecA	-
CSC54_RS12615 (CSC54_2282)	spxA	2412814..2413209 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
CSC54_RS12620 (CSC54_2283)	trpS	2413503..2414492 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
CSC54_RS12625 (CSC54_2284)	opp4C	2414534..2415415 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
CSC54_RS12630 (CSC54_2285)	opp4B	2415427..2416389 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=294648 CSC54_RS12605 WP_000959282.1 2410617..2411603(-) (coiA) [Staphylococcus aureus strain AR_0469]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=294648 CSC54_RS12605 WP_000959282.1 2410617..2411603(-) (coiA) [Staphylococcus aureus strain AR_0469]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976