Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EQY76_RS05180 Genome accession   NZ_CP035230
Coordinates   984873..985517 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis strain SRCM103551     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 979873..990517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQY76_RS05165 (EQY76_05165) glpD 980047..981714 (+) 1668 WP_021479678.1 glycerol-3-phosphate dehydrogenase -
  EQY76_RS05170 (EQY76_05170) pgcA 981844..983589 (+) 1746 WP_029726344.1 phosphoglucomutase -
  EQY76_RS05175 (EQY76_05175) yhcY 983738..984876 (+) 1139 Protein_942 two-component system sensor histidine kinase YhcY -
  EQY76_RS05180 (EQY76_05180) vraR 984873..985517 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  EQY76_RS05185 (EQY76_05185) yhdA 985514..986038 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  EQY76_RS05190 (EQY76_05190) yhdB 986053..986295 (-) 243 WP_003233373.1 YhdB family protein -
  EQY76_RS05195 (EQY76_05195) yhdC 986496..986819 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  EQY76_RS05200 (EQY76_05200) lytF 986861..988327 (-) 1467 WP_015252477.1 peptidoglycan endopeptidase LytF -
  EQY76_RS05205 (EQY76_05205) nsrR 988479..988919 (-) 441 WP_014479293.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=294490 EQY76_RS05180 WP_003245647.1 984873..985517(+) (vraR) [Bacillus subtilis strain SRCM103551]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=294490 EQY76_RS05180 WP_003245647.1 984873..985517(+) (vraR) [Bacillus subtilis strain SRCM103551]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411

Multiple sequence alignment