Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EQW70_RS17805 Genome accession   NZ_CP035226
Coordinates   3357237..3357872 (-) Length   211 a.a.
NCBI ID   WP_021480575.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103517     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3352237..3362872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQW70_RS17785 (EQW70_17785) yvzF 3353294..3353479 (-) 186 WP_003221676.1 YvzF family protein -
  EQW70_RS17790 (EQW70_17790) gerAA 3353597..3355045 (+) 1449 WP_032726836.1 spore germination receptor protein GerAA -
  EQW70_RS17795 (EQW70_17795) gerAB 3355014..3356111 (+) 1098 WP_021480573.1 spore germination receptor protein GerAB -
  EQW70_RS17800 (EQW70_17800) gerAC 3356108..3357229 (+) 1122 WP_021480574.1 spore germination receptor protein GerAC -
  EQW70_RS17805 (EQW70_17805) vraR 3357237..3357872 (-) 636 WP_021480575.1 two-component system response regulator LiaR Regulator
  EQW70_RS17810 (EQW70_17810) liaS 3357850..3358932 (-) 1083 WP_128740720.1 two-component system sensor histidine kinase LiaS -
  EQW70_RS17815 (EQW70_17815) liaF 3358929..3359654 (-) 726 WP_100505807.1 LiaRS two-component regulatory system accessory protein LiaF -
  EQW70_RS17820 (EQW70_17820) liaG 3359688..3360560 (-) 873 WP_128740721.1 DUF4097 domain-containing protein -
  EQW70_RS17825 (EQW70_17825) liaH 3360661..3361338 (-) 678 WP_015714684.1 stress responsive protein LiaH -
  EQW70_RS17830 (EQW70_17830) liaI 3361365..3361745 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23110.77 Da        Isoelectric Point: 5.0313

>NTDB_id=294284 EQW70_RS17805 WP_021480575.1 3357237..3357872(-) (vraR) [Bacillus subtilis strain SRCM103517]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAAELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVK

Nucleotide


Download         Length: 636 bp        

>NTDB_id=294284 EQW70_RS17805 WP_021480575.1 3357237..3357872(-) (vraR) [Bacillus subtilis strain SRCM103517]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGCGGAACTGTCGCCGGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTGACGAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACCAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCGCATCGAAATCATCTCGTCAAATAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.408