Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DK182_RS08855 Genome accession   NZ_CP029491
Coordinates   1808822..1810120 (-) Length   432 a.a.
NCBI ID   WP_019769629.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1803822..1815120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS08845 (DK181_08845) hpf 1807530..1808078 (-) 549 WP_002960280.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DK182_RS08850 (DK181_08850) - 1808154..1808822 (-) 669 WP_019769628.1 ComF family protein -
  DK182_RS08855 (DK181_08855) comFA/cflA 1808822..1810120 (-) 1299 WP_019769629.1 DEAD/DEAH box helicase Machinery gene
  DK182_RS08860 (DK181_08860) - 1810167..1810805 (+) 639 WP_109833666.1 YigZ family protein -
  DK182_RS08865 (DK181_08865) cysK 1810905..1811834 (+) 930 WP_019769631.1 cysteine synthase A -
  DK182_RS08870 (DK181_08870) - 1812053..1812403 (-) 351 WP_019771104.1 S1 RNA-binding domain-containing protein -
  DK182_RS08875 (DK181_08875) - 1812403..1813800 (-) 1398 WP_019771105.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DK182_RS08880 (DK181_08880) - 1813904..1814554 (-) 651 WP_019770084.1 response regulator -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49542.50 Da        Isoelectric Point: 10.2046

>NTDB_id=293229 DK182_RS08855 WP_019769629.1 1808822..1810120(-) (comFA/cflA) [Streptococcus sobrinus strain 10919]
MKDMKNYYGWQLTANQVPDDLRDKASVLPATIKKSGKYYCARCNHLLLPEWTLPDGSSYCRNCIVFGRLTTLDHLYYFEQ
KPFSKGAYLRWQGQLTPYQKEVSDILLEAVEKRENILVHAVTGSGKTEMIYRALANRLAKGKVVALVSPRIDVCRELYQR
LSRDFSCPISLLYANSEDYHRSPFLISTVHQLFKFRQAFDLIVIDEVDAFPFVDDQSLYHAVANALKPQGSKIFLTATST
DNLEKQVKKGQLREVHLARRFHANPLVSPSFVWLGDLDKKMTKGLIPVKLGQAIRQQRQTGFPLLLFYPTIVEGEQFARL
LQKYFPKEKIGFVSSRSQDRLELVQDFREGKLDILVSTTILERGVTFPKIDLFVLNAHHKLYTKSSLIQIAGRVGRSSKR
PNGLLRFYHSGVTRAMRRALQDIKLMNKKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=293229 DK182_RS08855 WP_019769629.1 1808822..1810120(-) (comFA/cflA) [Streptococcus sobrinus strain 10919]
ATGAAAGATATGAAAAATTACTATGGCTGGCAGTTGACTGCCAATCAAGTCCCGGACGACTTACGTGATAAGGCTTCGGT
CCTGCCTGCTACAATTAAAAAATCTGGGAAATATTACTGTGCTCGCTGCAACCATCTCTTATTGCCAGAGTGGACATTGC
CAGACGGTTCGTCTTATTGTCGCAACTGTATTGTTTTTGGCCGCTTGACCACTCTGGATCACCTTTATTATTTTGAGCAA
AAGCCTTTCAGCAAAGGAGCTTATCTGCGTTGGCAGGGACAATTAACGCCTTACCAGAAGGAAGTTTCAGATATTCTCCT
TGAAGCAGTTGAAAAAAGAGAAAATATTTTAGTTCATGCTGTTACGGGCTCAGGTAAGACCGAGATGATTTACCGTGCTC
TAGCCAATCGACTTGCTAAAGGAAAGGTAGTCGCTTTAGTTAGCCCAAGAATTGACGTTTGCCGTGAGCTTTATCAACGT
CTTAGTCGTGATTTTAGCTGTCCGATTTCCCTCTTATATGCCAATTCAGAAGACTATCACCGCTCTCCCTTTTTGATTTC
AACCGTCCATCAACTCTTTAAATTTCGCCAGGCCTTTGACCTCATTGTGATTGACGAGGTTGATGCCTTTCCTTTTGTGG
ACGATCAGAGCCTCTACCATGCCGTAGCCAATGCCCTCAAGCCCCAAGGGTCAAAAATCTTTCTGACAGCCACCTCAACT
GATAATTTAGAGAAACAAGTCAAGAAGGGGCAACTCAGAGAGGTTCATCTAGCCCGACGCTTCCATGCCAATCCCCTTGT
CTCGCCATCCTTTGTCTGGCTGGGGGATTTGGATAAAAAGATGACCAAGGGCTTAATTCCAGTCAAGCTTGGCCAGGCTA
TCCGTCAACAGAGACAAACAGGCTTTCCGCTTTTGCTTTTTTATCCGACGATTGTTGAGGGAGAGCAGTTTGCTCGTCTC
TTACAAAAATATTTTCCCAAGGAGAAGATTGGCTTTGTCTCCAGTCGCTCCCAAGACCGCTTGGAGCTAGTTCAAGACTT
TCGAGAGGGCAAGTTAGATATCCTAGTTTCGACGACAATTCTAGAAAGAGGGGTTACCTTCCCCAAAATTGATCTCTTTG
TTTTAAATGCTCACCATAAGCTTTATACAAAATCATCCCTGATTCAAATTGCTGGCCGCGTCGGACGCAGTAGTAAGCGA
CCAAATGGCCTCCTGCGATTTTACCACTCAGGGGTGACACGAGCCATGCGACGGGCTTTGCAGGATATTAAACTGATGAA
TAAAAAAGGAGGATTTTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

DEAD/DEAH box helicase (DEAD)

(96-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

54.63

100

0.546
  comFA/cflA Streptococcus pneumoniae Rx1

53.472

100

0.535
  comFA/cflA Streptococcus pneumoniae D39

53.472

100

0.535
  comFA/cflA Streptococcus pneumoniae R6

53.472

100

0.535
  comFA/cflA Streptococcus pneumoniae TIGR4

53.241

100

0.532
  comFA/cflA Streptococcus mitis NCTC 12261

53.241

100

0.532
  comFA Lactococcus lactis subsp. cremoris KW2

48.622

92.361

0.449
  comFA Latilactobacillus sakei subsp. sakei 23K

35.862

100

0.361

Multiple sequence alignment