Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DK182_RS05730 Genome accession   NZ_CP029491
Coordinates   1152167..1153399 (-) Length   410 a.a.
NCBI ID   WP_109833583.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1147167..1158399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS05700 (DK181_05700) - 1147193..1147405 (+) 213 Protein_1065 IS3 family transposase -
  DK182_RS05705 (DK181_05705) rplL 1147581..1147949 (-) 369 WP_002262825.1 50S ribosomal protein L7/L12 -
  DK182_RS05710 (DK181_05710) rplJ 1148022..1148522 (-) 501 WP_002961902.1 50S ribosomal protein L10 -
  DK182_RS05715 (DK181_05715) mmuM 1148852..1149823 (-) 972 WP_109833580.1 homocysteine S-methyltransferase -
  DK182_RS05720 (DK181_05720) - 1149877..1151250 (-) 1374 WP_109833581.1 amino acid permease -
  DK182_RS05725 (DK181_05725) yihA 1151558..1152157 (-) 600 WP_109833582.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DK182_RS05730 (DK181_05730) clpX 1152167..1153399 (-) 1233 WP_109833583.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DK182_RS10530 (DK181_05735) - 1153421..1153591 (-) 171 WP_094966435.1 hypothetical protein -
  DK182_RS05740 (DK181_05740) - 1153614..1154123 (-) 510 WP_019771146.1 dihydrofolate reductase -
  DK182_RS05745 (DK181_05745) - 1154207..1155046 (-) 840 WP_019775453.1 thymidylate synthase -
  DK182_RS05750 (DK181_05750) - 1155246..1156412 (+) 1167 WP_109833584.1 hydroxymethylglutaryl-CoA synthase -
  DK182_RS05755 (DK181_05755) - 1156418..1157329 (+) 912 WP_019777081.1 polysaccharide deacetylase family protein -
  DK182_RS05760 (DK181_05760) - 1157482..1158372 (-) 891 WP_002963151.1 lactate/malate family dehydrogenase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 44868.34 Da        Isoelectric Point: 4.3434

>NTDB_id=293215 DK182_RS05730 WP_109833583.1 1152167..1153399(-) (clpX) [Streptococcus sobrinus strain 10919]
MADNSTTNDTMVYCSFCGKNQTEVRKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLQILDDYVIGQV
QAKRALAVAVYNHYKRISFVESAQDEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIVEGTVASVPPQGGRKHPNQEMIQIDT
KNILFIVGGAFDGIEDIVKQRLGEKVIGFGQSNKSLDDDASYMQQIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVR
ILTEPKNALVKQYKTLLSYDGVDLEFDQEALEAIAQKAIERKTGARGLRSIIEETMMDIMFEVPSQEAVTSVEVTKAAVE
GTDKPILKTA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=293215 DK182_RS05730 WP_109833583.1 1152167..1153399(-) (clpX) [Streptococcus sobrinus strain 10919]
ATGGCAGACAATTCAACAACAAATGATACAATGGTCTATTGCTCATTTTGTGGAAAAAACCAGACAGAGGTCAGAAAAAT
AATTGCTGGTAACGGCGTTTTTATCTGTAATGAATGTGTGGCCCTCTCCCAAGAAATCATCAAAGAGGAGCTAGCTGAAG
AAGTTCTAGCTGACTTGGCGGAAGTTCCAAAACCCAAGGAACTCCTGCAAATCTTGGATGACTATGTTATCGGCCAAGTT
CAAGCAAAAAGAGCTCTGGCAGTTGCCGTTTATAACCATTACAAGCGAATCAGCTTTGTCGAGAGTGCCCAAGATGAGGA
TGTCGATTTGCAGAAATCTAATATTCTCATGATTGGCCCAACTGGTTCCGGTAAGACCTTCTTAGCTCAAACCTTGGCTA
AGAGTCTTAATGTTCCCTTTGCTATTGCGGATGCAACGGCCTTGACTGAAGCTGGATATGTCGGAGAAGATGTGGAGAAT
ATTCTTCTCAAACTGATTCAGGCTGCTGATTTCAATATTGAACGGGCTGAACGAGGCATCATCTATGTCGATGAAATTGA
CAAGATTGCCAAAAAGGGAGAAAATGTCTCCATTACTCGGGATGTCTCTGGTGAAGGGGTGCAACAGGCTCTCTTGAAAA
TTGTTGAAGGAACAGTTGCCAGTGTTCCACCACAAGGCGGGCGCAAGCACCCTAACCAAGAAATGATTCAGATTGACACC
AAGAACATCCTCTTTATTGTCGGAGGTGCCTTTGATGGTATCGAAGATATTGTTAAGCAACGCCTGGGTGAAAAGGTGAT
TGGTTTCGGTCAAAGCAATAAGTCTCTGGATGATGATGCTTCCTATATGCAACAAATTATTTCGGAGGATATTCAAAAAT
TTGGTCTCATTCCTGAATTTATCGGCCGTTTACCTGTCCTGGCTGCCCTTGAGCAGTTGACGGTTGACGATTTAGTGCGG
ATTCTGACTGAACCCAAGAACGCCTTGGTTAAACAGTATAAGACCCTTCTGTCTTATGATGGAGTGGATTTGGAATTTGA
TCAAGAAGCACTTGAAGCGATTGCTCAAAAGGCTATTGAGCGTAAGACTGGTGCTCGGGGCTTGCGTTCCATTATCGAAG
AAACCATGATGGACATCATGTTTGAAGTACCGAGTCAAGAAGCGGTTACTAGTGTTGAAGTAACCAAGGCAGCAGTTGAA
GGCACCGATAAACCTATCCTAAAGACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(13-49)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.512

100

0.895
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.357

97.805

0.561

Multiple sequence alignment