Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DK181_RS06295 Genome accession   NZ_CP029490
Coordinates   1301309..1302184 (-) Length   291 a.a.
NCBI ID   WP_002963077.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1296309..1307184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS06280 (DK182_06280) pheT 1296783..1299188 (-) 2406 WP_028798490.1 phenylalanine--tRNA ligase subunit beta -
  DK181_RS06285 (DK182_06285) - 1299317..1299838 (-) 522 WP_019769446.1 GNAT family N-acetyltransferase -
  DK181_RS06290 (DK182_06290) pheS 1299858..1300901 (-) 1044 WP_002963076.1 phenylalanine--tRNA ligase subunit alpha -
  DK181_RS06295 (DK182_06295) endA 1301309..1302184 (-) 876 WP_002963077.1 DNA/RNA non-specific endonuclease Machinery gene
  DK181_RS06300 (DK182_06300) - 1302239..1302430 (-) 192 WP_002963078.1 DNA-directed RNA polymerase subunit beta -
  DK181_RS06305 (DK182_06305) murA 1302430..1303698 (-) 1269 WP_002963079.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DK181_RS06310 (DK182_06310) - 1303762..1303998 (-) 237 WP_080566229.1 DUF1146 family protein -
  DK181_RS06315 (DK182_06315) - 1304351..1304770 (-) 420 WP_002963081.1 F0F1 ATP synthase subunit epsilon -
  DK181_RS06320 (DK182_06320) atpD 1304783..1306189 (-) 1407 WP_002963082.1 F0F1 ATP synthase subunit beta -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 31862.55 Da        Isoelectric Point: 10.0301

>NTDB_id=293166 DK181_RS06295 WP_002963077.1 1301309..1302184(-) (endA) [Streptococcus sobrinus strain SL1]
MVKKSKSSMKREQKALLSLIGLVLVLLLGFVATNDKISNQNPIKHVAQQLTGQNQGRRRSSSSQEAPTQTLADSVMTQEV
KNQLPEQMDWNGAGAYILNNNKTDLDAKVASNPYVNNQTKLIQGQTVPSQANALLAKSTRQYRNRQETGNGSTDWTPAGW
HQKTNLSGAYDHAVDRGHLIAYALAGSLKGFDASTSNPANVAVQTAWANEASSSQSTGQNYYETLIRKALDKNKRVRYRV
TLVYQEDNLIASGSHLEAKSSDGSLEFNVFIPNVQKGISLDYYSGQVSPKS

Nucleotide


Download         Length: 876 bp        

>NTDB_id=293166 DK181_RS06295 WP_002963077.1 1301309..1302184(-) (endA) [Streptococcus sobrinus strain SL1]
ATGGTGAAAAAATCAAAATCAAGCATGAAGCGAGAGCAAAAGGCCCTTTTGTCCCTAATCGGACTGGTATTGGTTCTGTT
ACTGGGCTTTGTGGCCACTAACGACAAGATTTCTAATCAGAATCCTATCAAGCATGTTGCCCAACAGTTGACTGGACAAA
ATCAAGGAAGAAGGCGCTCAAGTTCAAGCCAGGAGGCTCCAACTCAGACACTTGCTGACAGCGTTATGACCCAGGAAGTC
AAAAATCAGCTTCCGGAACAGATGGACTGGAATGGAGCAGGAGCCTACATTCTCAATAACAACAAGACCGATTTGGATGC
CAAGGTAGCCAGCAACCCCTATGTTAACAATCAAACCAAGCTGATCCAAGGGCAGACGGTTCCTAGTCAGGCCAATGCCC
TGCTGGCTAAATCTACCCGCCAGTACCGCAATCGTCAGGAGACTGGCAATGGCTCGACCGACTGGACCCCAGCTGGTTGG
CATCAAAAGACCAACCTCTCAGGAGCTTACGACCACGCAGTCGACCGGGGCCATCTGATTGCTTATGCCCTAGCTGGTAG
TCTTAAGGGCTTTGATGCCTCTACCAGCAATCCCGCCAATGTGGCGGTTCAGACCGCCTGGGCCAACGAGGCCAGCAGCT
CCCAGTCAACTGGTCAAAACTACTATGAAACCCTGATTCGTAAGGCCTTGGACAAAAACAAACGCGTCCGCTATCGGGTA
ACCTTGGTTTACCAAGAGGATAATCTGATTGCTTCTGGCAGTCATTTGGAAGCTAAGTCTTCCGACGGCAGTTTGGAATT
CAACGTCTTCATTCCCAATGTCCAAAAGGGTATCAGCCTAGATTATTATTCGGGACAGGTCTCACCCAAGTCCTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(125-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

65.778

77.32

0.509
  endA Streptococcus pneumoniae D39

65.778

77.32

0.509
  endA Streptococcus pneumoniae R6

65.778

77.32

0.509
  endA Streptococcus pneumoniae TIGR4

65.778

77.32

0.509

Multiple sequence alignment