Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DK181_RS05695 Genome accession   NZ_CP029490
Coordinates   1177577..1178809 (-) Length   410 a.a.
NCBI ID   WP_019781461.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1172577..1183809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS05665 (DK182_05665) - 1172603..1172815 (+) 213 Protein_1071 IS3 family transposase -
  DK181_RS05670 (DK182_05670) rplL 1172991..1173359 (-) 369 WP_002262825.1 50S ribosomal protein L7/L12 -
  DK181_RS05675 (DK182_05675) rplJ 1173432..1173932 (-) 501 WP_002961902.1 50S ribosomal protein L10 -
  DK181_RS05680 (DK182_05680) mmuM 1174262..1175233 (-) 972 WP_002961900.1 homocysteine S-methyltransferase -
  DK181_RS05685 (DK182_05685) - 1175287..1176660 (-) 1374 WP_028798387.1 amino acid permease -
  DK181_RS05690 (DK182_05690) yihA 1176968..1177567 (-) 600 WP_002961895.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DK181_RS05695 (DK182_05695) clpX 1177577..1178809 (-) 1233 WP_019781461.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DK181_RS10795 (DK182_05700) - 1178831..1179001 (-) 171 WP_002961893.1 hypothetical protein -
  DK181_RS05705 (DK182_05705) - 1179016..1179537 (-) 522 WP_002961892.1 dihydrofolate reductase -
  DK181_RS05710 (DK182_05710) - 1179621..1180460 (-) 840 WP_002961891.1 thymidylate synthase -
  DK181_RS05715 (DK182_05715) - 1180660..1181826 (+) 1167 WP_028798386.1 hydroxymethylglutaryl-CoA synthase -
  DK181_RS05720 (DK182_05720) - 1181832..1182743 (+) 912 WP_002961889.1 polysaccharide deacetylase family protein -
  DK181_RS05725 (DK182_05725) - 1182896..1183786 (-) 891 WP_002963151.1 lactate/malate family dehydrogenase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 44953.41 Da        Isoelectric Point: 4.3213

>NTDB_id=293165 DK181_RS05695 WP_019781461.1 1177577..1178809(-) (clpX) [Streptococcus sobrinus strain SL1]
MADNQTTNDTMVYCSFCGKNQTEVRKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLQILDDYVIGQV
QAKRALAVAVYNHYKRISFVESAQDEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIVEGTVASVPPQGGRKHPNQEMIQIDT
KNILFIVGGAFDGIEDIVKQRLGEKVIGFGQSNKSLDDDASYMQQIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVR
ILTEPKNALVKQYKTLLSYDGVDLEFDQEALEAIAQKAIERKTGARGLRSIIEETMMDIMFEVPSQEDVTSVEVTKAAVE
GTDKPILKTA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=293165 DK181_RS05695 WP_019781461.1 1177577..1178809(-) (clpX) [Streptococcus sobrinus strain SL1]
ATGGCAGACAATCAAACAACAAATGATACAATGGTCTATTGCTCATTTTGTGGAAAAAACCAGACAGAGGTCAGAAAAAT
AATTGCTGGTAACGGCGTTTTTATCTGTAATGAATGTGTGGCCCTCTCCCAAGAAATCATCAAAGAGGAGCTAGCTGAAG
AAGTTCTAGCTGACTTGGCGGAAGTTCCAAAACCCAAGGAACTCCTGCAAATCTTGGATGACTATGTTATCGGCCAAGTT
CAAGCAAAAAGAGCTCTGGCAGTTGCCGTTTATAACCATTACAAGCGAATCAGCTTTGTCGAGAGTGCCCAAGATGAGGA
TGTCGATTTGCAGAAATCTAATATTCTCATGATTGGCCCAACTGGTTCCGGTAAGACCTTCTTAGCTCAAACCTTGGCTA
AGAGTCTTAATGTTCCCTTTGCTATTGCGGATGCAACGGCCTTGACTGAAGCTGGATATGTCGGAGAAGATGTGGAGAAT
ATTCTTCTCAAACTGATTCAGGCTGCTGATTTCAATATTGAACGGGCTGAACGAGGCATCATCTATGTCGATGAAATTGA
CAAGATTGCCAAAAAGGGAGAAAATGTCTCCATTACTCGGGATGTCTCTGGTGAAGGGGTGCAACAGGCTCTCTTGAAAA
TTGTTGAAGGAACAGTTGCCAGTGTTCCACCACAAGGCGGGCGCAAGCACCCTAACCAAGAAATGATTCAGATTGACACC
AAGAACATCCTCTTTATTGTCGGAGGTGCCTTTGATGGTATCGAAGATATTGTTAAGCAACGCCTGGGTGAAAAGGTGAT
TGGTTTCGGTCAAAGCAATAAGTCTCTGGATGATGATGCTTCCTATATGCAACAAATTATTTCGGAGGATATTCAAAAAT
TTGGTCTCATTCCTGAATTTATCGGCCGTTTACCTGTCCTGGCTGCCCTTGAGCAGTTGACGGTTGACGATTTAGTGCGG
ATTCTGACTGAACCCAAGAACGCCTTGGTTAAACAGTATAAGACCCTTCTGTCTTATGATGGAGTGGATTTGGAATTTGA
TCAAGAAGCACTTGAAGCGATTGCTCAAAAGGCTATTGAGCGTAAGACTGGTGCTCGGGGCTTGCGTTCCATTATCGAAG
AAACCATGATGGACATCATGTTTGAAGTGCCTAGTCAAGAGGATGTTACCAGCGTTGAAGTGACAAAGGCGGCAGTTGAA
GGGACCGATAAGCCGATTCTCAAGACTGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(13-49)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.756

100

0.898
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

97.805

0.563

Multiple sequence alignment