Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DK181_RS02865 Genome accession   NZ_CP029490
Coordinates   554321..555013 (+) Length   230 a.a.
NCBI ID   WP_002959089.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 549321..560013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS02840 (DK182_02840) rsmG 550679..551392 (-) 714 WP_002959084.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DK181_RS02845 (DK182_02845) - 551917..552468 (+) 552 WP_002959085.1 LemA family protein -
  DK181_RS02850 (DK182_02850) htpX 552478..553374 (+) 897 WP_002959086.1 zinc metalloprotease HtpX -
  DK181_RS02855 (DK182_02855) - 553374..553577 (+) 204 WP_002959087.1 hypothetical protein -
  DK181_RS02860 (DK182_02860) - 553712..554248 (+) 537 WP_002959088.1 YceD family protein -
  DK181_RS02865 (DK182_02865) covR 554321..555013 (+) 693 WP_002959089.1 response regulator transcription factor Regulator
  DK181_RS02870 (DK182_02870) nrdR 555255..555752 (+) 498 WP_002959090.1 transcriptional regulator NrdR -
  DK181_RS02875 (DK182_02875) - 555739..556914 (+) 1176 WP_019770943.1 helicase DnaB -
  DK181_RS02880 (DK182_02880) dnaI 556915..557814 (+) 900 WP_002959092.1 primosomal protein DnaI -
  DK181_RS10785 - 557875..558042 (+) 168 WP_019768668.1 hypothetical protein -
  DK181_RS02885 (DK182_02885) der 558101..559411 (+) 1311 WP_002959093.1 ribosome biogenesis GTPase Der -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26475.51 Da        Isoelectric Point: 5.9283

>NTDB_id=293154 DK181_RS02865 WP_002959089.1 554321..555013(+) (covR) [Streptococcus sobrinus strain SL1]
MAKRILLIEGEKSLSRLVSLKLQERGYQTVVSQDGKSGLKTAMEKDFELIFIDLKLPDQDGLELMQELRGHKSVPVVLMV
GREDVATLLPKTDNLADDYLIKPFAVEELLDKVDETFQRKDFKRRKQSTSQTTAYQDLILDEANRSVIRKGESIALTKRE
FALLSTLLRHINMVMTREELLDYVWSYSDGTIETNVVDVYVRYLRGKIDIPGQESYIQTVRGLGYVIRER

Nucleotide


Download         Length: 693 bp        

>NTDB_id=293154 DK181_RS02865 WP_002959089.1 554321..555013(+) (covR) [Streptococcus sobrinus strain SL1]
ATGGCAAAACGCATTCTATTGATTGAAGGCGAAAAAAGTTTATCACGTTTGGTATCCTTAAAACTACAGGAAAGGGGCTA
TCAAACAGTTGTCAGTCAAGATGGGAAATCAGGCTTAAAAACAGCCATGGAAAAGGATTTTGAACTGATTTTTATTGATT
TAAAACTCCCAGACCAAGATGGTTTGGAACTGATGCAGGAACTCAGGGGACATAAATCTGTACCAGTTGTCCTGATGGTT
GGTCGGGAAGATGTAGCAACCCTTCTCCCTAAAACTGACAACTTGGCCGATGATTATTTGATTAAGCCCTTTGCGGTGGA
AGAATTACTTGATAAGGTTGATGAAACCTTTCAGCGAAAAGATTTTAAACGCCGGAAGCAATCAACCAGCCAGACAACAG
CTTATCAAGATTTGATTTTGGATGAGGCTAACCGCTCAGTTATTCGCAAAGGGGAGTCCATTGCTCTGACTAAAAGAGAG
TTTGCTTTGCTATCAACTCTTTTACGGCATATCAATATGGTGATGACCCGTGAGGAGTTGTTAGATTATGTCTGGAGTTA
TAGTGATGGGACAATTGAGACCAATGTTGTTGATGTTTACGTACGCTATCTTCGAGGTAAGATTGATATCCCTGGCCAAG
AATCTTATATTCAAACCGTGCGAGGTCTGGGTTATGTGATTCGTGAGCGTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

54.783

100

0.548
  covR Lactococcus lactis subsp. lactis strain DGCC12653

49.345

99.565

0.491

Multiple sequence alignment