Detailed information NTG0292991

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DKK89_RS08545
• Genome accession: NZ_CP029474
• Coordinates: 1666704..1667690 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain USA 100 isolate 30-47
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1661704..1672690

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DKK89_RS08520 (DKK89_08510)	opp4B	1661917..1662879 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
DKK89_RS08525 (DKK89_08515)	opp4C	1662891..1663772 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
DKK89_RS08530 (DKK89_08520)	trpS	1663814..1664803 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
DKK89_RS08535 (DKK89_08525)	spxA	1665097..1665492 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
DKK89_RS08540 (DKK89_08530)	mecA	1665863..1666582 (+)	720	WP_001217728.1	adaptor protein MecA	-
DKK89_RS08545 (DKK89_08535)	coiA	1666704..1667690 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
DKK89_RS08550 (DKK89_08540)	pepF	1667738..1669546 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
DKK89_RS08555 (DKK89_08545)	yjbH	1670006..1670812 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
DKK89_RS08560 (DKK89_08550)	-	1670835..1671200 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
DKK89_RS08565 (DKK89_08555)	-	1671304..1671897 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
DKK89_RS08570 (DKK89_08560)	-	1672083..1672430 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=292991 DKK89_RS08545 WP_000959282.1 1666704..1667690(+) (coiA) [Staphylococcus aureus strain USA 100 isolate 30-47]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=292991 DKK89_RS08545 WP_000959282.1 1666704..1667690(+) (coiA) [Staphylococcus aureus strain USA 100 isolate 30-47]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976