Detailed information NTG0292645

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: EQH95_RS00595
• Genome accession: NZ_CP035162
• Coordinates: 108671..109753 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain SRCM103886
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 103671..114753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH95_RS00580 (EQH95_00580)	mcsB	103679..104770 (+)	1092	WP_003235007.1	protein arginine kinase	-
EQH95_RS00585 (EQH95_00585)	clpC	104767..107199 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
EQH95_RS00590 (EQH95_00590)	radA/sms	107291..108667 (+)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
EQH95_RS00595 (EQH95_00595)	disA	108671..109753 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
EQH95_RS00600 (EQH95_00600)	yacL	109869..110969 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
EQH95_RS00605 (EQH95_00605)	ispD	110984..111682 (+)	699	WP_069837191.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
EQH95_RS00610 (EQH95_00610)	ispF	111675..112151 (+)	477	WP_069837192.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
EQH95_RS00615 (EQH95_00615)	gltX	112242..113693 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
EQH95_RS00625 (EQH95_00625)	cysE	113995..114648 (+)	654	WP_014478618.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=292645 EQH95_RS00595 WP_003225736.1 108671..109753(+) (disA) [Bacillus subtilis strain SRCM103886]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=292645 EQH95_RS00595 WP_003225736.1 108671..109753(+) (disA) [Bacillus subtilis strain SRCM103886]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTCCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1