Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DF184_RS08155 Genome accession   NZ_CP029398
Coordinates   1637147..1637836 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain HN105     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1632147..1642836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS08130 (DF184_08130) - 1632617..1633330 (-) 714 WP_109371794.1 NADPH-dependent oxidoreductase -
  DF184_RS08135 (DF184_08135) dnaI 1633327..1634226 (-) 900 WP_109371796.1 primosomal protein DnaI -
  DF184_RS08140 (DF184_08140) - 1634226..1635377 (-) 1152 WP_109371798.1 replication initiation/membrane attachment protein -
  DF184_RS08145 (DF184_08145) nrdR 1635364..1635855 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  DF184_RS08150 (DF184_08150) - 1635927..1637057 (-) 1131 WP_024412190.1 AI-2E family transporter -
  DF184_RS08155 (DF184_08155) covR 1637147..1637836 (-) 690 WP_002942700.1 winged helix-turn-helix domain-containing protein Regulator
  DF184_RS08160 (DF184_08160) gndA 1637918..1639345 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  DF184_RS08165 (DF184_08165) - 1639442..1639981 (-) 540 WP_014736258.1 DUF177 domain-containing protein -
  DF184_RS08170 (DF184_08170) trxB 1639991..1640908 (-) 918 WP_109371800.1 thioredoxin-disulfide reductase -
  DF184_RS08175 (DF184_08175) - 1640922..1641146 (-) 225 WP_002936682.1 DUF4059 family protein -
  DF184_RS08180 (DF184_08180) - 1641164..1642507 (-) 1344 WP_024406634.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=292289 DF184_RS08155 WP_002942700.1 1637147..1637836(-) (covR) [Streptococcus suis strain HN105]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=292289 DF184_RS08155 WP_002942700.1 1637147..1637836(-) (covR) [Streptococcus suis strain HN105]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGCGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGTCCAGAACCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment