Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DG474_RS08000 Genome accession   NZ_CP029257
Coordinates   1647633..1648322 (-) Length   229 a.a.
NCBI ID   WP_255778025.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1642633..1653322
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS07980 (DG474_08110) mvaD 1643558..1644511 (-) 954 WP_000375374.1 diphosphomevalonate decarboxylase -
  DG474_RS07985 (DG474_08115) mvk 1644493..1645371 (-) 879 WP_255778022.1 mevalonate kinase -
  DG474_RS07990 (DG474_08120) cbpC 1645489..1646508 (-) 1020 WP_255778023.1 choline-binding protein CbpC -
  DG474_RS07995 (DG474_08125) cbpJ 1646526..1647533 (-) 1008 WP_255778024.1 choline-binding protein CbpJ -
  DG474_RS08000 (DG474_08130) covR 1647633..1648322 (-) 690 WP_255778025.1 response regulator transcription factor Regulator
  DG474_RS08005 (DG474_08135) gndA 1648334..1649758 (-) 1425 WP_000158772.1 NADP-dependent phosphogluconate dehydrogenase -
  DG474_RS08010 (DG474_08140) - 1649834..1651279 (-) 1446 WP_044021314.1 cell division site-positioning protein MapZ family protein -
  DG474_RS08015 (DG474_08145) - 1651292..1652449 (-) 1158 WP_255778026.1 class I SAM-dependent RNA methyltransferase -
  DG474_RS08025 (DG474_08155) gpsB 1652935..1653264 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26857.09 Da        Isoelectric Point: 8.0271

>NTDB_id=291432 DG474_RS08000 WP_255778025.1 1647633..1648322(-) (covR) [Streptococcus oralis strain CCUG 53468]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQMDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=291432 DG474_RS08000 WP_255778025.1 1647633..1648322(-) (covR) [Streptococcus oralis strain CCUG 53468]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTTGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGATGGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCAGCTTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATTGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment