Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A1D75_RS06245 Genome accession   NZ_CP034806
Coordinates   1293088..1293744 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 2010C-3347     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1288088..1298744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A1D75_RS06210 dcyD 1288967..1289953 (+) 987 WP_001128225.1 D-cysteine desulfhydrase -
  A1D75_RS06215 tcyL 1289968..1290636 (+) 669 WP_001158226.1 cystine ABC transporter permease -
  A1D75_RS06220 tcyN 1290633..1291385 (+) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  A1D75_RS06225 sdiA 1291615..1292337 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  A1D75_RS06230 yecF 1292405..1292629 (-) 225 WP_000106479.1 DUF2594 family protein YecF -
  A1D75_RS06235 yecU 1292616..1292792 (-) 177 WP_001302050.1 protein YecU -
  A1D75_RS29950 - 1292830..1292946 (-) 117 WP_001302039.1 hypothetical protein -
  A1D75_RS06245 letA 1293088..1293744 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  A1D75_RS06250 uvrC 1293741..1295573 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  A1D75_RS06255 pgsA 1295630..1296178 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A1D75_RS06275 - 1297170..1297451 (+) 282 WP_001303543.1 hypothetical protein -
  A1D75_RS06280 - 1297472..1297666 (+) 195 WP_115801851.1 hypothetical protein -
  A1D75_RS06285 - 1297608..1298741 (+) 1134 WP_032161728.1 IS30-like element IS30 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=291298 A1D75_RS06245 WP_000611328.1 1293088..1293744(+) (letA) [Escherichia coli strain 2010C-3347]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=291298 A1D75_RS06245 WP_000611328.1 1293088..1293744(+) (letA) [Escherichia coli strain 2010C-3347]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482