Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AYP37_RS04645 Genome accession   NZ_CP034797
Coordinates   773648..774304 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 08-3918     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 768648..779304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AYP37_RS04615 yecA 769900..770565 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  AYP37_RS04635 pgsA 771214..771762 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AYP37_RS04640 uvrC 771819..773651 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AYP37_RS04645 letA 773648..774304 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AYP37_RS29370 - 774446..774562 (+) 117 WP_001302039.1 hypothetical protein -
  AYP37_RS04655 yecU 774600..774776 (+) 177 WP_001302050.1 protein YecU -
  AYP37_RS04660 yecF 774763..774987 (+) 225 WP_000106478.1 DUF2594 family protein YecF -
  AYP37_RS04665 sdiA 775055..775777 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  AYP37_RS04670 tcyN 776007..776759 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AYP37_RS04675 tcyL 776756..777424 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  AYP37_RS04680 dcyD 777439..778425 (-) 987 WP_001128225.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=290969 AYP37_RS04645 WP_000611328.1 773648..774304(-) (letA) [Escherichia coli strain 08-3918]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=290969 AYP37_RS04645 WP_000611328.1 773648..774304(-) (letA) [Escherichia coli strain 08-3918]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482