Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A1D74_RS11770 Genome accession   NZ_CP034794
Coordinates   2268553..2269209 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 06-3462     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2263553..2274209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A1D74_RS11730 - 2264234..2264689 (-) 456 Protein_2255 transposase -
  A1D74_RS11735 - 2264631..2264825 (-) 195 WP_115801851.1 hypothetical protein -
  A1D74_RS11740 - 2264846..2265127 (-) 282 WP_001303543.1 hypothetical protein -
  A1D74_RS11760 pgsA 2266119..2266667 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A1D74_RS11765 uvrC 2266724..2268556 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  A1D74_RS11770 letA 2268553..2269209 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  A1D74_RS29175 - 2269351..2269467 (+) 117 WP_001302039.1 hypothetical protein -
  A1D74_RS11780 yecU 2269505..2269681 (+) 177 WP_001302050.1 protein YecU -
  A1D74_RS11785 yecF 2269668..2269892 (+) 225 WP_000106478.1 DUF2594 family protein YecF -
  A1D74_RS11790 sdiA 2269960..2270682 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  A1D74_RS11795 tcyN 2270912..2271664 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  A1D74_RS11800 tcyL 2271661..2272329 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  A1D74_RS11805 dcyD 2272344..2273330 (-) 987 WP_001128225.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=290906 A1D74_RS11770 WP_000611328.1 2268553..2269209(-) (letA) [Escherichia coli strain 06-3462]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=290906 A1D74_RS11770 WP_000611328.1 2268553..2269209(-) (letA) [Escherichia coli strain 06-3462]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482