Detailed information NTG0290749

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: C3363_RS00940
• Genome accession: NZ_CP029150
• Coordinates: 183380..184576 (+)
• Length: 398 a.a.
• NCBI ID: WP_005711777.1
• Uniprot ID: B8F826
• Organism: Glaesserella parasuis strain GZ20170512
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 178380..189576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C3363_RS00920 (C3363_00940)	radA	178995..180371 (-)	1377	WP_010787009.1	DNA repair protein RadA	-
C3363_RS00925 (C3363_00945)	pilA	180559..181011 (+)	453	WP_010787008.1	pilin	Machinery gene
C3363_RS00930 (C3363_00950)	-	181284..181649 (+)	366	WP_015940027.1	endonuclease domain-containing protein	-
C3363_RS00935 (C3363_00955)	pilB	182002..183387 (+)	1386	WP_010787006.1	GspE/PulE family protein	Machinery gene
C3363_RS00940 (C3363_00960)	pilC	183380..184576 (+)	1197	WP_005711777.1	type II secretion system F family protein	Machinery gene
C3363_RS00945 (C3363_00965)	-	184573..185241 (+)	669	WP_010787005.1	prepilin peptidase	-
C3363_RS00950 (C3363_00970)	dapE	185325..186458 (+)	1134	WP_010787004.1	succinyl-diaminopimelate desuccinylase	-
C3363_RS00955 (C3363_00975)	clpX	186532..187782 (-)	1251	WP_005711769.1	ATP-dependent protease ATP-binding subunit ClpX	-
C3363_RS00960 (C3363_00980)	clpP	187789..188370 (-)	582	WP_010787003.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
C3363_RS00965 (C3363_00985)	-	188471..188860 (+)	390	WP_010787002.1	SufE family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45575.38 Da
• Isoelectric Point: 10.1129

>NTDB_id=290749 C3363_RS00940 WP_005711777.1 183380..184576(+) (pilC) [Glaesserella parasuis strain GZ20170512]
MNNIYEFQWKGRNRFGQKQTGRQLAESREVLEKRLQQKGYSQLSISRHFALPTAPKKEEINQFMQQLALLIQAKIPLKQS
LVMLLETCQNRTFYRWQQETIRLIEAGFALSVAFKKQGKYINPQEIQLIKMAETSGNLGLILTNIAQRREKSEKLAKKIK
KILFYPVFILAISITLSILLLLFIVPQFAELYGSKGKSLPLITEILFSLSHFLQHSILTLIILCVLCFLLIHILNKKTDL
IKRLKFIILSHIPILKGIIQYSRIIFFCQNSSLMLASHIRLDTVLHSFLANKSDDILLQGSLATTLTYLKQGYRLADSLD
PKLFPTDMLQMIAIGEQSGKLSPMLQQISDGYQQRLDYQIDILSQLLEPMLMVLMGIIVGTILVGLYLPIFDMGAMIE

Nucleotide

• Length: 1197 bp

>NTDB_id=290749 C3363_RS00940 WP_005711777.1 183380..184576(+) (pilC) [Glaesserella parasuis strain GZ20170512]
ATGAATAACATTTATGAATTTCAATGGAAAGGACGCAACCGCTTTGGGCAAAAGCAGACAGGGCGACAGCTTGCCGAAAG
CCGAGAAGTGCTAGAGAAACGGTTGCAACAAAAAGGATACAGCCAGTTAAGCATTAGCCGACATTTTGCCTTGCCGACTG
CACCAAAAAAGGAAGAAATTAATCAATTTATGCAACAGTTAGCCTTATTAATTCAAGCTAAAATCCCCCTAAAACAGAGT
TTAGTGATGTTGCTTGAAACCTGCCAAAATCGCACTTTTTACCGTTGGCAACAAGAAACAATCCGCTTGATTGAAGCCGG
CTTTGCGTTATCCGTTGCCTTTAAAAAACAGGGAAAATATATTAATCCACAAGAAATCCAATTAATTAAAATGGCAGAAA
CAAGCGGTAATTTAGGGCTAATTTTAACCAACATTGCACAACGCCGTGAAAAATCGGAAAAATTAGCCAAGAAAATTAAA
AAAATTCTCTTTTATCCCGTCTTTATTTTAGCTATTTCAATCACACTCTCTATTTTATTATTGCTTTTTATTGTGCCACA
ATTTGCAGAACTTTATGGTTCAAAAGGAAAATCACTCCCTCTAATTACCGAAATACTCTTTAGCCTATCCCATTTTCTAC
AACACTCTATTTTAACGCTAATTATTTTATGTGTATTATGTTTTCTATTAATTCATATTTTAAATAAAAAAACAGATCTT
ATTAAACGCCTAAAGTTTATTATATTAAGCCATATTCCTATTTTAAAAGGCATTATCCAGTATTCACGCATTATCTTTTT
TTGTCAAAATAGCAGTTTAATGCTGGCTTCACATATTCGTTTAGATACTGTACTTCATTCCTTTTTAGCCAATAAAAGCG
ATGATATTTTATTACAAGGTTCTCTAGCAACTACACTAACTTATTTAAAACAAGGCTATCGTTTAGCCGACAGTTTAGAT
CCAAAACTCTTTCCTACGGATATGTTACAGATGATTGCCATTGGCGAGCAGAGCGGAAAATTATCGCCAATGTTGCAACA
AATCAGCGACGGTTATCAACAGCGGTTAGATTATCAAATTGATATACTTTCCCAATTATTAGAGCCGATGTTAATGGTGT
TAATGGGAATTATTGTAGGAACTATTTTAGTCGGGTTATATTTGCCGATTTTTGATATGGGAGCAATGATAGAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-186)

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

3D structure

• AlphaFold DB: B8F826

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	100	100	1
pilC	Haemophilus influenzae 86-028NP	38.155	100	0.384
pilC	Haemophilus influenzae Rd KW20	38.155	100	0.384