Detailed information NTG0029065

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SGO_RS03210
• Genome accession: NC_009785
• Coordinates: 697105..698148 (+)
• Length: 347 a.a.
• NCBI ID: WP_012000130.1
• Uniprot ID: A8AVZ5
• Organism: Streptococcus gordonii str. Challis substr. CH1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 692105..703148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGO_RS03175 (SGO_0645)	-	692644..692937 (-)	294	WP_012000123.1	DUF5960 family protein	-
SGO_RS03180 (SGO_0646)	-	692915..693289 (-)	375	WP_012000124.1	hypothetical protein	-
SGO_RS03185 (SGO_0647)	-	693286..694701 (-)	1416	WP_012000125.1	Y-family DNA polymerase	-
SGO_RS03190 (SGO_0648)	-	694705..695382 (-)	678	WP_012000126.1	helix-turn-helix domain-containing protein	-
SGO_RS03195 (SGO_0649)	-	695525..696013 (+)	489	WP_012000127.1	YcxB family protein	-
SGO_RS03200 (SGO_0650)	rsmD	696086..696634 (+)	549	WP_172601498.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SGO_RS03205 (SGO_0651)	coaD	696624..697118 (+)	495	WP_012000129.1	pantetheine-phosphate adenylyltransferase	-
SGO_RS03210 (SGO_0652)	sepM	697105..698148 (+)	1044	WP_012000130.1	SepM family pheromone-processing serine protease	Regulator
SGO_RS03215 (SGO_0653)	-	698320..698856 (+)	537	WP_012000131.1	YutD family protein	-
SGO_RS03220 (SGO_0654)	rlmN	698866..699954 (+)	1089	WP_012000132.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SGO_RS03225 (SGO_0655)	-	699941..700480 (+)	540	WP_012000133.1	VanZ family protein	-
SGO_RS03230 (SGO_0656)	trpB	700846..702027 (+)	1182	WP_002907062.1	tryptophan synthase subunit beta	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38051.60 Da
• Isoelectric Point: 6.1221

>NTDB_id=29065 SGO_RS03210 WP_012000130.1 697105..698148(+) (sepM) [Streptococcus gordonii str. Challis substr. CH1]
MRKISVYKWPIIIFSSLILLVVSLTVPLPYYIEVPGGAEDIRKVLLVDNKEDKEAGAYEFVTVGVQRATFAHLVYAWLTD
FTDIYSAEEMTGGSSDQEFIRINQFYMETSQNMAKYQGLKTAGKDISMKYLGVYVLQVAKDSTFKGILNIADTVTGVNDK
TFDSSEELVKYVNSQKLGDKVKVTYQEDGQEKSATGKIIKLENGKNGIGISLIDRTEVTSNIPIEFTTEGIGGPSAGLMF
SLSIYTQLADPTLRDGRVIAGTGSINRDGEVGDIGGIDKKVVSAAKSGASIFFAPNNPVTKEMKKIDPKAKTNYETAVEA
AKKIKTDMKIVPVKTLQDAIDYLKNNK

Nucleotide

• Length: 1044 bp

>NTDB_id=29065 SGO_RS03210 WP_012000130.1 697105..698148(+) (sepM) [Streptococcus gordonii str. Challis substr. CH1]
ATGAGAAAAATTAGTGTTTATAAATGGCCCATTATCATTTTTTCAAGCTTGATTTTGCTTGTCGTATCTTTGACGGTTCC
TTTACCATACTATATTGAAGTTCCTGGCGGTGCAGAGGATATTCGAAAGGTCTTGCTGGTTGATAATAAGGAAGATAAGG
AAGCTGGGGCTTACGAGTTTGTGACAGTTGGAGTTCAACGAGCAACCTTTGCTCATCTTGTCTATGCGTGGCTGACTGAT
TTCACGGATATCTACTCTGCTGAAGAAATGACTGGTGGATCATCGGACCAAGAATTTATTCGAATCAATCAGTTTTATAT
GGAAACATCCCAAAACATGGCCAAGTATCAAGGTTTGAAAACGGCTGGAAAAGATATTAGCATGAAATATCTGGGCGTCT
ATGTTTTGCAAGTCGCAAAAGATTCGACTTTTAAGGGAATTTTGAATATTGCGGACACGGTAACGGGAGTTAATGACAAG
ACTTTTGACAGTTCAGAAGAATTGGTGAAATATGTTAATTCGCAGAAATTAGGAGATAAGGTTAAGGTCACTTACCAAGA
AGATGGACAAGAAAAATCTGCTACTGGAAAGATTATTAAGCTAGAAAATGGTAAAAACGGAATTGGTATTAGCTTAATTG
ATAGAACAGAAGTTACTAGTAACATTCCAATTGAATTTACTACAGAAGGCATTGGAGGACCTAGTGCGGGTCTCATGTTT
AGCTTGTCAATCTATACACAACTTGCAGATCCAACCTTACGAGATGGACGTGTGATTGCAGGTACCGGAAGTATCAATCG
TGATGGAGAAGTTGGTGATATTGGAGGGATTGATAAGAAAGTCGTCTCAGCTGCTAAAAGTGGTGCCAGCATCTTCTTTG
CTCCCAATAATCCTGTAACAAAAGAAATGAAAAAAATCGATCCAAAAGCAAAGACAAACTATGAAACTGCAGTTGAGGCT
GCTAAAAAGATTAAAACAGATATGAAAATTGTTCCTGTTAAAACCTTACAGGATGCCATTGATTATCTTAAGAACAATAA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A8AVZ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.983	99.712	0.608