Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EKM58_RS13545 Genome accession   NZ_CP034589
Coordinates   2786079..2786735 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain L37     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2781079..2791735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM58_RS13510 (EKM58_13510) - 2782209..2782949 (+) 741 WP_106661694.1 hypothetical protein -
  EKM58_RS13535 (EKM58_13535) pgsA 2783645..2784193 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EKM58_RS13540 (EKM58_13540) uvrC 2784250..2786082 (-) 1833 WP_001283412.1 excinuclease ABC subunit UvrC Machinery gene
  EKM58_RS13545 (EKM58_13545) letA 2786079..2786735 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EKM58_RS24630 - 2786877..2786948 (+) 72 Protein_2649 transcriptional regulator -
  EKM58_RS13550 (EKM58_13550) yecU 2787031..2787207 (+) 177 WP_000590347.1 protein YecU -
  EKM58_RS13555 (EKM58_13555) yecF 2787194..2787418 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EKM58_RS13560 (EKM58_13560) sdiA 2787485..2788207 (-) 723 WP_001152713.1 transcriptional regulator SdiA -
  EKM58_RS13565 (EKM58_13565) tcyN 2788437..2789189 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EKM58_RS13570 (EKM58_13570) tcyL 2789186..2789854 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EKM58_RS13575 (EKM58_13575) dcyD 2789869..2790855 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=290263 EKM58_RS13545 WP_000611335.1 2786079..2786735(-) (letA) [Escherichia coli strain L37]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=290263 EKM58_RS13545 WP_000611335.1 2786079..2786735(-) (letA) [Escherichia coli strain L37]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486