Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EJ992_RS15115 Genome accession   NZ_CP034569
Coordinates   2894542..2896314 (-) Length   590 a.a.
NCBI ID   WP_011198178.1    Uniprot ID   Q65GF0
Organism   Bacillus licheniformis strain ATCC 14580     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2889542..2901314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJ992_RS15090 (EJ992_15090) sdhA 2889724..2891487 (-) 1764 WP_003184180.1 succinate dehydrogenase flavoprotein subunit -
  EJ992_RS15095 (EJ992_15095) - 2891521..2892129 (-) 609 WP_003184182.1 succinate dehydrogenase cytochrome b558 subunit -
  EJ992_RS15100 (EJ992_15100) - 2892431..2892874 (+) 444 WP_003184184.1 YslB family protein -
  EJ992_RS15105 (EJ992_15105) - 2892919..2894148 (-) 1230 WP_011198177.1 aspartate kinase -
  EJ992_RS15115 (EJ992_15115) uvrC 2894542..2896314 (-) 1773 WP_011198178.1 excinuclease ABC subunit UvrC Machinery gene
  EJ992_RS15120 (EJ992_15120) trxA 2896457..2896771 (-) 315 WP_003184189.1 thioredoxin -
  EJ992_RS15125 (EJ992_15125) - 2896984..2897961 (-) 978 WP_009329334.1 electron transfer flavoprotein subunit alpha/FixB family protein -
  EJ992_RS15130 (EJ992_15130) - 2898011..2898784 (-) 774 WP_003184191.1 electron transfer flavoprotein subunit beta/FixA family protein -
  EJ992_RS15135 (EJ992_15135) - 2898816..2899592 (-) 777 WP_009329335.1 enoyl-CoA hydratase -
  EJ992_RS15140 (EJ992_15140) - 2899595..2900197 (-) 603 WP_003184196.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 590 a.a.        Molecular weight: 68398.37 Da        Isoelectric Point: 9.4622

>NTDB_id=290183 EJ992_RS15115 WP_011198178.1 2894542..2896314(-) (uvrC) [Bacillus licheniformis strain ATCC 14580]
MNKKIKEKLALLPDQPGCYLMKDRQDTVIYVGKAKILKNRVRSYFSGSHDAKTQRLVSEIEDFEYIVTSSNIEALILEMN
LIKKYDPKYNVMLKDDKSYPFIKITNERHPKLVVTRKVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCAKLPDRVCL
YYHLGQCLAPCVYDVSEETNRQLTEEITRFLKGGYNEVKKELEAKMLEASENLQFERAKEFRDQIAHIESTMEKQKMMLN
DMVDRDVFAYSYDKGWMCVQVFFIRQGKLIERDVSMFPLYREADEEFLTFIGQFYSKNNHFLPKEILVPDSVDKDMIEEL
LDVNVRQPKRGAKKDLLLLAHKNAKLALKEKFSLIERDEERTIGAIEKLGKALDIYTPYRIEAFDNSNIQGTDPVSAMVV
FLDGKPHKKEYRKYKIKTVEGPDDYGSMREVIRRRYTRVLKENLPLPDLILIDGGKGQVSAALDVLENELGLDVPVAGLV
KDDKHRTSNLLIGDPLEIVQLERNSQEFYLLQRIQDEVHRFAISFHRQLRGKSAFQSVLDGIPGVGEQRKKLLLKHFGSV
KKMKEASAEDIRKLGIPLKTAQLIEEALKK

Nucleotide


Download         Length: 1773 bp        

>NTDB_id=290183 EJ992_RS15115 WP_011198178.1 2894542..2896314(-) (uvrC) [Bacillus licheniformis strain ATCC 14580]
ATGAACAAAAAAATCAAAGAAAAGCTGGCCCTTCTTCCGGATCAGCCTGGCTGCTACTTGATGAAAGACAGGCAGGATAC
CGTCATCTACGTCGGGAAAGCGAAAATCTTAAAAAACAGGGTCCGCTCCTATTTCAGCGGGTCCCATGATGCCAAAACAC
AGCGTCTTGTCAGTGAAATTGAAGACTTCGAATACATTGTCACATCCTCGAACATCGAAGCGCTCATTCTTGAAATGAAT
TTAATCAAAAAGTACGACCCGAAATATAACGTGATGCTTAAAGATGATAAAAGCTACCCGTTCATTAAAATCACGAACGA
GCGGCATCCGAAGCTGGTTGTCACAAGGAAGGTCAAAAAAGACAAAGGCCGCTATTTCGGGCCGTACCCCAATGTCCAGG
CTGCGAGGGAAACAAAAAAGCTGCTGGACCGCCTCTATCCGCTCAGAAAGTGCGCCAAGCTGCCTGACCGCGTCTGTTTG
TACTATCATCTCGGACAATGTCTGGCGCCATGCGTATATGATGTGTCTGAGGAGACAAACAGACAGCTCACAGAAGAAAT
TACCCGCTTTTTAAAAGGCGGCTACAATGAAGTGAAGAAAGAGCTTGAAGCAAAAATGCTCGAAGCCTCGGAAAACCTGC
AGTTTGAACGGGCGAAAGAATTCCGCGATCAAATTGCCCATATCGAGTCAACGATGGAAAAACAGAAAATGATGCTGAAT
GACATGGTTGACCGCGATGTATTTGCCTATTCGTATGACAAGGGCTGGATGTGCGTCCAGGTCTTCTTCATCAGGCAGGG
CAAATTGATTGAAAGAGATGTCAGCATGTTTCCTTTATACAGGGAAGCAGACGAGGAATTTCTGACATTCATCGGGCAAT
TTTACTCCAAAAACAACCATTTTCTTCCGAAGGAAATTTTGGTGCCTGACAGCGTCGACAAGGACATGATTGAGGAGCTT
TTGGACGTGAACGTGCGCCAGCCGAAAAGAGGAGCGAAAAAAGACCTGCTGCTCCTTGCCCATAAAAATGCAAAGCTCGC
TTTGAAGGAGAAGTTTTCGCTCATTGAACGGGATGAAGAGCGGACGATCGGCGCGATTGAAAAGCTCGGAAAAGCGCTGG
ACATCTACACGCCATACAGAATTGAAGCGTTTGATAACTCAAATATTCAAGGAACGGACCCTGTTTCGGCCATGGTTGTA
TTTCTCGATGGAAAACCGCATAAAAAAGAGTACCGCAAATATAAGATCAAGACGGTTGAAGGTCCTGACGACTACGGATC
AATGCGCGAAGTCATCAGAAGAAGATATACAAGGGTGCTGAAAGAGAATCTGCCGCTGCCTGATTTAATTTTGATCGACG
GCGGAAAGGGGCAGGTGTCTGCCGCCCTTGACGTTCTGGAAAATGAACTGGGTCTCGATGTCCCTGTTGCCGGTCTGGTG
AAAGACGATAAGCACAGAACATCCAACCTTTTGATCGGCGATCCCCTTGAGATCGTCCAGCTTGAGCGGAACAGCCAGGA
ATTTTACCTGCTTCAGCGCATTCAGGACGAAGTGCACAGGTTTGCGATCAGCTTCCACAGGCAGCTCAGGGGAAAAAGCG
CATTTCAATCGGTGCTGGACGGCATACCGGGCGTCGGCGAACAGCGGAAAAAACTGCTGTTAAAACATTTCGGTTCCGTT
AAGAAAATGAAGGAAGCGAGCGCCGAAGATATCCGCAAGCTCGGCATACCTCTGAAAACGGCGCAGCTGATCGAAGAGGC
ATTGAAAAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(377-523)

UvrB/uvrC motif (UVR)

(197-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65GF0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

60.374

99.661

0.602
  uvrC Streptococcus pneumoniae R6

60.034

99.661

0.598
  uvrC Streptococcus pneumoniae D39

60.034

99.661

0.598

Multiple sequence alignment