Detailed information NTG0290166

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSC50_RS05090
• Genome accession: NZ_CP029082
• Coordinates: 990405..991292 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AR465
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 985405..996292

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC50_RS05060 (CSC50_0911)	-	986137..986898 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
CSC50_RS05065 (CSC50_0912)	-	987143..987598 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSC50_RS15730	-	987720..987821 (+)	102	WP_000731976.1	SE2200 family small protein	-
CSC50_RS05075 (CSC50_0913)	-	987881..989305 (-)	1425	WP_000953755.1	alkaline phosphatase	-
CSC50_RS05080 (CSC50_0914)	-	989503..989703 (+)	201	WP_000604730.1	hypothetical protein	-
CSC50_RS05085 (CSC50_0915)	braR	989729..990394 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSC50_RS05090 (CSC50_0916)	braS	990405..991292 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSC50_RS05095 (CSC50_0917)	-	991400..992155 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSC50_RS05100 (CSC50_0918)	-	992152..994152 (+)	2001	WP_000776750.1	ABC transporter permease	-
CSC50_RS05105	-	994811..994924 (+)	114	Protein_924	hypothetical protein	-
CSC50_RS05115	-	995306..995566 (+)	261	WP_001791974.1	hypothetical protein	-
CSC50_RS05120 (CSC50_0919)	-	995576..996073 (+)	498	WP_001065268.1	glutathione peroxidase	-
CSC50_RS05125	-	996181..996273 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=290166 CSC50_RS05090 WP_000143425.1 990405..991292(+) (braS) [Staphylococcus aureus strain AR465]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=290166 CSC50_RS05090 WP_000143425.1 990405..991292(+) (braS) [Staphylococcus aureus strain AR465]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1