Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   CSC51_RS10690 Genome accession   NZ_CP029080
Coordinates   2111782..2112468 (-) Length   228 a.a.
NCBI ID   WP_072468915.1    Uniprot ID   A0A5F0HFN7
Organism   Staphylococcus aureus strain AR466     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2106782..2117468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC51_RS10670 (CSC51_1967) rpsT 2107696..2107947 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  CSC51_RS10675 (CSC51_1968) holA 2107992..2108966 (-) 975 WP_001282573.1 DNA polymerase III subunit delta -
  CSC51_RS10680 (CSC51_1969) comEC 2109023..2111224 (-) 2202 WP_001622275.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  CSC51_RS10685 (CSC51_1970) - 2111229..2111690 (-) 462 WP_000439693.1 ComE operon protein 2 -
  CSC51_RS10690 (CSC51_1971) comEA 2111782..2112468 (-) 687 WP_072468915.1 ComEA family DNA-binding protein Machinery gene
  CSC51_RS10695 (CSC51_1972) - 2112508..2113224 (-) 717 WP_000084840.1 class I SAM-dependent methyltransferase -
  CSC51_RS10700 (CSC51_1973) rsfS 2113227..2113580 (-) 354 WP_001088020.1 ribosome silencing factor -
  CSC51_RS10705 (CSC51_1974) yqeK 2113581..2114165 (-) 585 WP_001017837.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  CSC51_RS10710 (CSC51_1975) nadD 2114155..2114724 (-) 570 WP_000725165.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  CSC51_RS10715 (CSC51_1976) yhbY 2114727..2115017 (-) 291 WP_108703200.1 ribosome assembly RNA-binding protein YhbY -
  CSC51_RS10720 (CSC51_1977) aroE 2115021..2115827 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  CSC51_RS10725 (CSC51_1978) yqeH 2115841..2116941 (-) 1101 WP_001280146.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25812.41 Da        Isoelectric Point: 9.3305

>NTDB_id=290139 CSC51_RS10690 WP_072468915.1 2111782..2112468(-) (comEA) [Staphylococcus aureus strain AR466]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQAKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGENSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=290139 CSC51_RS10690 WP_072468915.1 2111782..2112468(-) (comEA) [Staphylococcus aureus strain AR466]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGCCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACACCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGAAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HFN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment