Detailed information NTG0289779

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: EJF26_RS06545
• Genome accession: NZ_CP034442
• Coordinates: 1295951..1298485 (-)
• Length: 844 a.a.
• NCBI ID: WP_000206070.1
• Uniprot ID: -
• Organism: Streptococcus oralis subsp. dentisani strain F0392
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1290951..1303485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJF26_RS06520	ruvA	1291454..1292047 (-)	594	WP_000273426.1	Holliday junction branch migration protein RuvA	Machinery gene
EJF26_RS06525	-	1292207..1292704 (+)	498	WP_025168986.1	helix-turn-helix domain-containing protein	-
EJF26_RS06530	hexB	1292855..1294804 (-)	1950	WP_000018190.1	DNA mismatch repair endonuclease MutL	Machinery gene
EJF26_RS06535	-	1295015..1295455 (+)	441	WP_000861950.1	LytTR family DNA-binding domain-containing protein	-
EJF26_RS06540	-	1295452..1295910 (+)	459	WP_000743965.1	DUF3021 domain-containing protein	-
EJF26_RS06545	hexA	1295951..1298485 (-)	2535	WP_000206070.1	DNA mismatch repair protein MutS	Machinery gene
EJF26_RS06550	argR	1298536..1298982 (-)	447	WP_001227365.1	arginine repressor	-
EJF26_RS06555	argS	1299130..1300818 (+)	1689	WP_000104866.1	arginine--tRNA ligase	-
EJF26_RS06560	-	1301299..1301544 (+)	246	WP_000084854.1	hypothetical protein	-
EJF26_RS06565	-	1301740..1303002 (+)	1263	WP_000084740.1	NRAMP family divalent metal transporter	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94798.26 Da
• Isoelectric Point: 4.8876

>NTDB_id=289779 EJF26_RS06545 WP_000206070.1 1295951..1298485(-) (hexA) [Streptococcus oralis subsp. dentisani strain F0392]
MTTEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAINAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVAIDRDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDIHLLDSRLAAVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIIQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELESLISTAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSQIDIQKGRHAVVEKVMGAQTYIPNTIQMTEDISIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPAELLARADKILTQLESQGTESPAPMRQTSA
VTEQMSLFDAPEEHPILAELAKLDVYNMTPMQAMNVLVEFKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=289779 EJF26_RS06545 WP_000206070.1 1295951..1298485(-) (hexA) [Streptococcus oralis subsp. dentisani strain F0392]
ATGACGACAGAAAAACTATCACCTGGTATGCAGCAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGGATGGGTGATTTTTATGAGCTGTTTTACGAAGATGCGATCAATGCGGCACAGATTTTAGAGATTTCACTGACCAGTC
GTAATAAAAATGCAGAAAATCCGATACCCATGGCGGGCGTCCCCTATCATTCTGCCCAGCAGTATATTGATGTTTTGATT
GAGCAGGGCTATAAGGTGGCCATTGCCGAGCAGATGGAAGATCCCAAACAAGCAGTTGGGGTTGTTAAGCGAGAGGTGGT
TCAGGTCATCACACCAGGTACAGTCGTTGATAGCAGTAAGCCGGATAGTCAGAACAATTTCTTGGTTGCCATAGATCGTG
ATGGCAATCAATTTGGCCTGGCTTATATGGACCTGGTGACGGGTGATTTTTATGTGACGGGTCTATTGGACTTTACCCTC
GTTTGTGGGGAAATTCGCAATCTCAAGGCTCGTGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGTCGTCAGATGAATCTGGTACTTTCCTACGAGAAAGAAGGCTTTGAGGACATTCATTTACTGGATTCACGTTTAGCAG
CTGTGGAGCAAGCGGCAGCTAGTAAGCTGCTTCAGTATGTCCACCGTACCCAGATGCGGGAATTGAATCATCTTAAACCG
GTAATTCGTTATGAAATCAAAGATTTCTTGCAGATGGATTATGCGACCAAGGCCAGTCTGGATCTGGTAGAGAATGCTCG
TTCAGGCAAGAAGCAGGGGAGTCTTTTCTGGCTTTTGGATGAAACCAAAACGGCTATGGGTATGCGGCTCTTACGCTCTT
GGATCCATCGTCCCTTGATTGATAAGGAACGAATCATCCAACGTCAAGAGGTGGTGCAGGTCTTTCTTGACCACTTCTTT
GAGCGTAGTGATTTGACGGACAGTCTCAAAGGTGTTTATGACATCGAACGCTTGGCTAGTCGAGTTTCCTTTGGTAAGAC
CAATCCCAAGGATCTCTTGCAGTTGGCGACCACCTTATCCAGTGTGCCACGGATTCGTGCGATTTTAGAAGGCATGGAGC
AGCCTGCTCTAGCCTACCTCATCGCACAGTTGGATGCCATCCCTGAGTTGGAGAGTTTGATTAGTACTGCCATTGCTCCT
GAAGCCCCTCACGTTATTACGGAAGGTGGCATTATCCGTACGGGATTTGATGAGACCTTAGACAAGTACCGTCGTGTGCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGAGAAAACTCTGGCATCAGCACGCTTAAGATTGACT
ACAATAAAAAGGATGGCTATTATTTCCATGTGACCAATTCACAACTGGGAAATGTTCCTGCCCACTTTTTCCGCAAGGCG
ACGTTGAAAAACTCCGAACGTTTTGGAACTGAGGAGTTGGCGCGTATTGAGGGAGATATGTTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAATACGAAATCTTTATGCGTATTCGTGAAGAAGTCAGCAAGTACATTCAGCGTTTGCAGGCTCTAGCCC
AAGGAATTGCGACAGTTGATGTCTTGCAAAGTCTAGCAGTTGTAGCTGAAACCCAGCATTTGATTCGACCTGAGTTTGGG
GATGATTCACAAATCGATATCCAGAAAGGGCGCCATGCTGTCGTTGAAAAGGTCATGGGAGCCCAGACCTATATTCCTAA
TACGATTCAGATGACAGAAGACATCAGTATTCAATTGATTACAGGGCCCAACATGAGCGGGAAGTCTACCTACATGCGTC
AGCTAGCCATGACGGCGGTTATGGCCCAGCTAGGTTCTTATGTGCCGGCAGAGAGCGCCCATTTGCCTATCTTCGATGCC
ATCTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCAGGTCAATCAACCTTTATGGTGGAGATGATGGAGGCCAATAA
TGCCATTTCGCATGCGACCAAGAACTCTCTCATTCTCTTTGATGAATTGGGACGTGGGACTGCAACTTATGACGGGATGG
CTCTTGCCCAGTCCATCATCGAATACATTCATGAACATATCGGAGCCAAAACTCTCTTTGCCACTCACTATCATGAGTTG
ACTAGTCTGGAGTCCAGCCTGGAACACTTGGTCAATGTCCATGTGGCAACCTTGGAGCAGGATGGGCAGGTAACCTTCCT
TCACAAGATCGAACCAGGGCCAGCTGACAAATCCTACGGTATCCACGTTGCCAAGATCGCTGGTTTACCAGCAGAACTTT
TAGCAAGGGCGGATAAGATATTAACTCAACTGGAGAGTCAAGGGACGGAAAGCCCTGCTCCCATGAGACAAACGAGTGCT
GTTACTGAACAGATGTCACTCTTTGATGCGCCTGAAGAACATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTACAA
CATGACACCTATGCAGGCTATGAATGTCTTAGTTGAGTTCAAACAAAAGTTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	96.327	100	0.963
mutS	Pseudomonas stutzeri strain ATCC 17587	36.756	100	0.373