Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EJF26_RS06530 Genome accession   NZ_CP034442
Coordinates   1292855..1294804 (-) Length   649 a.a.
NCBI ID   WP_000018190.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1287855..1299804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS06500 - 1288579..1289256 (+) 678 WP_000078007.1 DUF1129 domain-containing protein -
  EJF26_RS06505 - 1289395..1290429 (+) 1035 WP_000255131.1 S66 peptidase family protein -
  EJF26_RS06510 - 1290535..1290798 (+) 264 WP_000166112.1 SemiSWEET family transporter -
  EJF26_RS06515 - 1290881..1291444 (-) 564 WP_000166571.1 DNA-3-methyladenine glycosylase I -
  EJF26_RS06520 ruvA 1291454..1292047 (-) 594 WP_000273426.1 Holliday junction branch migration protein RuvA Machinery gene
  EJF26_RS06525 - 1292207..1292704 (+) 498 WP_025168986.1 helix-turn-helix domain-containing protein -
  EJF26_RS06530 hexB 1292855..1294804 (-) 1950 WP_000018190.1 DNA mismatch repair endonuclease MutL Machinery gene
  EJF26_RS06535 - 1295015..1295455 (+) 441 WP_000861950.1 LytTR family DNA-binding domain-containing protein -
  EJF26_RS06540 - 1295452..1295910 (+) 459 WP_000743965.1 DUF3021 domain-containing protein -
  EJF26_RS06545 hexA 1295951..1298485 (-) 2535 WP_000206070.1 DNA mismatch repair protein MutS Machinery gene
  EJF26_RS06550 argR 1298536..1298982 (-) 447 WP_001227365.1 arginine repressor -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73418.94 Da        Isoelectric Point: 5.6206

>NTDB_id=289778 EJF26_RS06530 WP_000018190.1 1292855..1294804(-) (hexB) [Streptococcus oralis subsp. dentisani strain F0392]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASAKKMIAIENSDLDFEISGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKERELMALVSE
AISNSLKEQALIPDALENLAKSTVRNRQKVEQTILPLKENMLYYEKTELSRPNQVEVADHQVVLTEEGRDLTLFAKETLD
QLTRPAKLHFAERKPTNYDQLDHPELDLASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKDRMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=289778 EJF26_RS06530 WP_000018190.1 1292855..1294804(-) (hexB) [Streptococcus oralis subsp. dentisani strain F0392]
ATGTCTCATATTATTGAATTACCAGAGGTGCTGGCAAACCAGATCGCGGCAGGAGAGGTCATTGAACGTCCTGCCAGTGT
GGTCAAAGAGTTGGTAGAAAATGCCATTGACGCGGGTTCTAGCCAGATTATCATCGAGATTGAGGAAGCTGGTCTCAAGA
AAATCCAAATCACCGATAATGGTCATGGAATTGCCCACGATGAGGTGGAATTGGCCCTGCGACGTCATGCTACCAGTAAG
ATAAAAAATCAGGCAGATCTCTTTCGGATTCGGACGCTTGGTTTTCGTGGTGAAGCCCTGCCTTCTATCGCTTCTGTTAG
TGTCTTGACTCTGTTGACGGCGGTGGATGGTGCGAGTCATGGGACCAAGCTCGTTGCGCGTGGGGGTGAAGTTGAGGAAG
TCATCCCAGCGACTAGTCCTGTGGGGACCAAAGTTTGTGTGGAGGATCTCTTTTTCAACACGCCAGCCCGTCTCAAGTAT
ATGAAGAGCCAGCAAGCGGAGCTGTCCCATATCATTGATATTGTCAACCGTCTGGGCTTGGCCCATCCCGAGATTTCTTT
TAGTTTAATCAGTGATGGCAAGGAAATGACACGAACAGCTGGAACTGGTCAACTGCGACAAGCCATCGCAGGAATTTATG
GTTTGGCGAGTGCTAAGAAGATGATTGCCATTGAGAACTCTGACCTAGATTTCGAAATTTCAGGATTTGTGTCATTGCCT
GAGTTGACTCGGGCCAACCGCAACTATATCAGTCTCTTCATCAATGGCCGTTATATCAAGAACTTCCTGCTCAATCGTGC
CATTTTAGATGGTTATGGAAGCAAACTTATGGTGGGGCGTTTTCCACTGGCAGTCATTCACATCCATATCGACCCTTATC
TGGCTGATGTCAATGTTCATCCAACCAAACAAGAAGTGCGGATTTCTAAGGAAAGAGAACTAATGGCGCTGGTTTCAGAA
GCTATTTCTAACAGTCTCAAAGAGCAAGCCTTGATCCCTGATGCTTTGGAAAACCTTGCCAAATCTACTGTGCGTAATCG
TCAAAAGGTGGAGCAGACCATTCTCCCACTCAAAGAAAATATGCTCTATTACGAAAAAACAGAACTCTCAAGACCCAATC
AAGTTGAGGTGGCTGATCATCAGGTCGTGTTAACTGAGGAGGGTAGGGACCTAACCTTGTTTGCCAAGGAAACCTTGGAC
CAGCTGACTAGACCAGCAAAACTGCATTTTGCAGAGAGAAAGCCTACTAACTACGACCAACTAGACCATCCAGAGTTAGA
TCTTGCTAGTCTCGATAAGGCCTATGATAAGCTGGAGCGAGAAGAATCATCCAGCTTCCCAGAGTTGGAGTTTTTCGGGC
AAATGCACGGGACCTATCTTTTTGCCCAAGGGCGAGATGGGCTCTACATCATAGACCAGCACGCGGCTCAGGAACGGGTT
AAGTACGAGGAATATCGTGAAAGCATCGGCAATGTTGACCAGAGCCAGCAGCAACTCCTAGTGCCCTACATCTTTGAATT
TCCAGCGGATGATGCCCTTCGTCTCAAGGATAGAATGCCTCTCTTAGAGGAAGTGGGCGTCTTTCTAGCAGAGTACGGAG
AAAATCAATTTATCCTGCGTGAACATCCTATTTGGATGGCAGAGGAGGAGATTGAGTCAGGCATCTATGAAATGTGTGAC
ATGCTACTCTTGACCAAGGAAGTTTCTATCAAAAAATACCGAGCAGAGCTGGCTATCATGATGTCCTGCAAACGGTCTAT
CAAGGCCAACCATCGCATCGATGACCACTCAGCCAGACAACTCCTTTATCAGCTTTCTCAATGTGACAATCCCTATAACT
GTCCTCATGGACGTCCCGTTTTGGTGCATTTTACCAAGTCAGATATGGAAAAAATGTTCCGACGTATTCAGGAAAATCAT
ACTAGTCTCCGTGAGTTAGGGAAATATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(450-592)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

96.302

100

0.963