Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EJC75_RS15965 Genome accession   NZ_CP034404
Coordinates   2867392..2868024 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CRE10     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2862392..2873024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJC75_RS15940 (EJC75_15940) yheS 2862561..2864474 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  EJC75_RS15945 (EJC75_15945) yheT 2864474..2865496 (+) 1023 WP_000057410.1 hydrolase -
  EJC75_RS15950 (EJC75_15950) yheU 2865490..2865708 (+) 219 WP_000907085.1 YheU family protein -
  EJC75_RS15955 (EJC75_15955) prkB 2865762..2866631 (+) 870 WP_001274683.1 phosphoribulokinase -
  EJC75_RS15960 (EJC75_15960) yhfA 2866686..2867090 (-) 405 WP_001148908.1 OsmC family protein -
  EJC75_RS15965 (EJC75_15965) crp 2867392..2868024 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EJC75_RS15970 (EJC75_15970) yhfK 2868075..2870165 (+) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  EJC75_RS15975 (EJC75_15975) argD 2870232..2871452 (-) 1221 WP_000963797.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EJC75_RS15980 (EJC75_15980) pabA 2871538..2872101 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EJC75_RS15985 (EJC75_15985) fic 2872141..2872741 (-) 601 Protein_2744 putative adenosine monophosphate-protein transferase Fic -
  EJC75_RS15990 (EJC75_15990) - 2872788..2872896 (-) 109 Protein_2745 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=289490 EJC75_RS15965 WP_000242755.1 2867392..2868024(+) (crp) [Escherichia coli strain CRE10]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=289490 EJC75_RS15965 WP_000242755.1 2867392..2868024(+) (crp) [Escherichia coli strain CRE10]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment