Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DC427_RS08660 Genome accession   NZ_CP029030
Coordinates   1700989..1701675 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain CAR     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1695989..1706675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DC427_RS08640 rpsT 1696903..1697154 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  DC427_RS08645 holA 1697199..1698173 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  DC427_RS08650 comEC 1698230..1700431 (-) 2202 WP_001548978.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DC427_RS08655 - 1700436..1700897 (-) 462 WP_000439693.1 ComE operon protein 2 -
  DC427_RS08660 comEA 1700989..1701675 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  DC427_RS08665 - 1701715..1702431 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  DC427_RS08670 rsfS 1702434..1702787 (-) 354 WP_001088022.1 ribosome silencing factor -
  DC427_RS08675 yqeK 1702788..1703372 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DC427_RS08680 nadD 1703362..1703931 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  DC427_RS08685 yhbY 1703934..1704224 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  DC427_RS08690 aroE 1704228..1705034 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  DC427_RS08695 yqeH 1705048..1706148 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=289372 DC427_RS08660 WP_001792568.1 1700989..1701675(-) (comEA) [Staphylococcus aureus strain CAR]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=289372 DC427_RS08660 WP_001792568.1 1700989..1701675(-) (comEA) [Staphylococcus aureus strain CAR]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment