Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EJH97_RS10205 Genome accession   NZ_CP034389
Coordinates   2100146..2100802 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RS571     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2095146..2105802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJH97_RS10175 (EJH97_10175) dcyD 2096026..2097012 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  EJH97_RS10180 (EJH97_10180) tcyL 2097027..2097695 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EJH97_RS10185 (EJH97_10185) tcyN 2097692..2098444 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EJH97_RS10190 (EJH97_10190) sdiA 2098674..2099396 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  EJH97_RS10195 (EJH97_10195) yecF 2099463..2099687 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EJH97_RS10200 (EJH97_10200) yecU 2099674..2099850 (-) 177 WP_000590347.1 protein YecU -
  EJH97_RS10205 (EJH97_10205) letA 2100146..2100802 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EJH97_RS10210 (EJH97_10210) uvrC 2100799..2102631 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EJH97_RS10215 (EJH97_10215) pgsA 2102688..2103236 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EJH97_RS10235 (EJH97_10235) yecA 2103886..2104551 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=289357 EJH97_RS10205 WP_000611328.1 2100146..2100802(+) (letA) [Escherichia coli strain RS571]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=289357 EJH97_RS10205 WP_000611328.1 2100146..2100802(+) (letA) [Escherichia coli strain RS571]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482