Detailed information NTG0289088

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: D1J63_RS16280
• Genome accession: NZ_CP034353
• Coordinates: 3695418..3696542 (+)
• Length: 374 a.a.
• NCBI ID: WP_030404779.1
• Uniprot ID: A0A6B3QRH4
• Organism: Streptomyces sp. KPB2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3690418..3701542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1J63_RS16255 (D1J63_16255)	-	3690482..3691294 (+)	813	WP_125629503.1	hypothetical protein	-
D1J63_RS37560	-	3691371..3691499 (+)	129	WP_276323134.1	hypothetical protein	-
D1J63_RS36905	-	3691592..3693373 (-)	1782	WP_206436771.1	hypothetical protein	-
D1J63_RS16275 (D1J63_16275)	radA/sms	3693927..3695336 (+)	1410	WP_102932190.1	DNA repair protein RadA	Machinery gene
D1J63_RS16280 (D1J63_16280)	disA	3695418..3696542 (+)	1125	WP_030404779.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
D1J63_RS36730	-	3696563..3697408 (-)	846	WP_206436772.1	hypothetical protein	-
D1J63_RS16295 (D1J63_16295)	-	3697567..3698493 (+)	927	WP_125629511.1	A/G-specific adenine glycosylase	-
D1J63_RS16300 (D1J63_16300)	-	3698792..3699325 (+)	534	WP_003975479.1	SigE family RNA polymerase sigma factor	-
D1J63_RS16305 (D1J63_16305)	-	3699313..3699990 (+)	678	WP_176154385.1	hypothetical protein	-
D1J63_RS16310 (D1J63_16310)	cseB	3700116..3700820 (+)	705	WP_102930763.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40084.82 Da
• Isoelectric Point: 5.0058

>NTDB_id=289088 D1J63_RS16280 WP_030404779.1 3695418..3696542(+) (disA) [Streptomyces sp. KPB2]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=289088 D1J63_RS16280 WP_030404779.1 3695418..3696542(+) (disA) [Streptomyces sp. KPB2]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACGGGCGGTCTGATCGTGC
TGGGCTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGTTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCCGACCTGTCGAAGATCCTGCGGGCCGGGGTGCAGCTCCTTCC
GGATCCCACCATTCCGACGGAGGAGACCGGTACGCGGCACCGGACCGCCGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TCGTGTCGGTCTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGATTCGGCGGCC
ATTCTGTCGCGGGCCAATCAGGCACTGGCGACCCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCGCGCTGCAGTTGGACGAGCTGATCGCC
GGGGTGGAGCCCGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCGGAGCCGACCGCCAAGCGGTCCCGTACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCACGCGGAACTGCTGGAACTGTCGACCGTGGCCCGGGCCCTGGGCTACACCG
GGTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTGCAGACCGTGGA
CGGCGTCGGTGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A6B3QRH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447