Detailed information NTG0288541

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EHC66_RS13405
• Genome accession: NZ_CP034294
• Coordinates: 2723756..2726329 (-)
• Length: 857 a.a.
• NCBI ID: WP_005460310.1
• Uniprot ID: Q87S63
• Organism: Vibrio parahaemolyticus strain 20140829008-1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2718756..2731329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHC66_RS13405 (EHC66_13610)	clpC	2723756..2726329 (-)	2574	WP_005460310.1	ATP-dependent chaperone ClpB	Regulator
EHC66_RS13410 (EHC66_13615)	pgeF	2726477..2727205 (-)	729	WP_005460314.1	peptidoglycan editing factor PgeF	-
EHC66_RS13415 (EHC66_13620)	rluD	2727207..2728184 (-)	978	WP_005460300.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EHC66_RS13420 (EHC66_13625)	comL	2728321..2729049 (+)	729	WP_020904194.1	outer membrane protein assembly factor BamD	Machinery gene
EHC66_RS13425 (EHC66_13630)	-	2729184..2730665 (+)	1482	WP_322107826.1	lytic transglycosylase F	-
EHC66_RS13430 (EHC66_13635)	hpf	2730996..2731322 (+)	327	WP_005468590.1	ribosome hibernation-promoting factor, HPF/YfiA family	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95872.46 Da
• Isoelectric Point: 5.1096

>NTDB_id=288541 EHC66_RS13405 WP_005460310.1 2723756..2726329(-) (clpC) [Vibrio parahaemolyticus strain 20140829008-1]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLDVDVTHLRSKLGEMLDRLPKVSGIGGD
VQLSSSMGTLFNLCDKVAQKRQDSYISSEVFLLAALEDRGPLGQLLKEVGLTEQKVSQAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIVNNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNVILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTVAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRLQIDSKPESLDKLERKIIQLKIEQQALSNEHDEASEKRLQALNDELNEKEREYAELEEVWNTEKAALSGTQHIKSELE
QARMDMEFARRAGDLNRMSELQYGRIPELEKQLDLATQAEMQEMTLLRNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHNRVVGQSEAVAVVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLASFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFATLDYQGIKSEVMDVVSKHFRPEFLNRVDEIVVFHPLGQEHIKSIASIQLERLAKRLEEKGYQLEVSDKAL
DLIAQVGFDPVYGARPLKRAIQQNVENPLAKSILAGEIVPDKKVQLIVTNDQILAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=288541 EHC66_RS13405 WP_005460310.1 2723756..2726329(-) (clpC) [Vibrio parahaemolyticus strain 20140829008-1]
ATGCGTCTTGATAGATTTACCAGTAAGTTTCAAATCGCTATCTCTGATGCTCAATCACTAGCGTTAGGGCGCGATCATCA
GTACATCGAGCCAGTTCACTTAATGGTGGCTTTGCTTGATCAAAATGGCAGTCCAATTCGTCCATTGCTGACAATGCTGG
ACGTGGATGTAACTCATCTCCGCTCAAAGCTGGGCGAAATGCTTGATCGATTACCAAAGGTGAGTGGCATCGGTGGTGAT
GTGCAGCTTTCTAGCTCGATGGGGACTTTGTTCAATCTGTGTGACAAAGTGGCTCAAAAGCGTCAAGACTCCTACATCTC
GTCCGAAGTCTTCTTGCTTGCGGCATTAGAAGATCGTGGTCCTTTAGGGCAACTACTTAAAGAAGTAGGGCTGACCGAGC
AAAAAGTGAGTCAAGCGATTGAAAAGATCAGAGGTGGTCAAAAGGTCAATGATCCAAATGCTGAAGAGCTACGTCAGGCT
CTTGAAAAATTCACCATCGATTTAACTGAGCGAGCTGAGCAGGGCAAATTGGATCCTGTAATTGGTCGAGATGATGAAAT
TCGTCGCACGATTCAAGTATTGCAACGTCGCACTAAAAACAACCCAGTGATCATCGGTGAGCCTGGTGTGGGTAAAACCG
CAATTGTGGAAGGCTTGGCGCAGCGAATCGTTAATAACGAAGTGCCTGAAGGTCTACGCGGTCGCCGTGTTCTATCACTG
GATATGGGCGCACTTGTTGCTGGCGCGAAATACCGTGGTGAATTTGAAGAGCGTTTAAAATCAGTATTGAATGAACTTGC
TAAAGAAGAAGGCAACGTCATCCTCTTCATTGATGAACTACACACTATGGTCGGCGCTGGTAAAGGTGAAGGCTCAATGG
ATGCGGGCAACATGCTCAAACCAGCATTGGCTCGCGGCGAACTTCACTGTGTTGGTGCAACAACATTGGATGAGTACCGT
CAATACATCGAAAAGGATGCTGCATTAGAACGTCGTTTCCAAAAAGTGCTGGTGGATGAGCCGACAGTAGAAGATACGGT
AGCTATTCTTCGTGGTCTGAAAGAGCGTTATGAACTTCATCACCATGTAGAAATTACTGACCCAGCGATTGTTGCAGCGG
CAAGTTTGTCGCACCGTTATATTTCGGACCGTCAGTTGCCAGATAAAGCCATTGACTTGATCGATGAAGCGGCTTCAAGC
ATTCGTCTACAAATCGATTCAAAACCAGAATCATTAGATAAGCTTGAGCGTAAAATCATCCAACTAAAAATTGAGCAACA
AGCACTAAGTAACGAGCACGATGAAGCGAGTGAAAAGCGTCTGCAAGCATTGAATGATGAGTTGAATGAGAAAGAACGCG
AATACGCAGAGTTAGAAGAAGTTTGGAATACAGAAAAAGCCGCACTTTCTGGTACTCAGCATATTAAATCTGAACTAGAG
CAAGCTCGCATGGACATGGAGTTTGCGCGTCGGGCTGGTGATCTAAACCGAATGTCTGAGCTTCAATACGGTCGTATTCC
GGAATTAGAGAAGCAACTAGATTTGGCGACTCAGGCTGAAATGCAAGAAATGACGCTGCTTCGTAACAAAGTAACAGATA
ACGAAATCGCAGAAGTGCTTTCTAAACAAACGGGCATTCCAGTATCTAAGATGTTAGAAGCGGAGAAAGAGAAACTACTT
CGCATGGAAGATGTGCTTCACAATCGTGTTGTAGGGCAAAGCGAAGCAGTTGCAGTGGTATCGAATGCGATTCGTCGTAG
CCGAGCTGGGCTTTCTGATCCAAACCGACCAATTGGTTCCTTCTTATTCTTAGGTCCAACTGGTGTCGGTAAAACGGAAT
TATGTAAGACACTTGCGAGCTTCATGTTCGACAGTGAAGATGCAATGGTACGTATCGACATGTCGGAGTTCATGGAGAAA
CACTCAGTAGCAAGATTAGTGGGTGCGCCTCCAGGTTACGTTGGTTACGAAGAGGGGGGGTATCTAACTGAAGCGGTTCG
TCGAAAACCATACTCAGTGATCTTGTTGGATGAAGTAGAAAAAGCACATCCAGATGTGTTCAATATTCTTCTGCAGGTGC
TTGATGATGGCCGACTCACTGATGGACAAGGTCGTACGGTTGATTTTCGTAACACCGTCGTGATCATGACATCAAACTTG
GGTTCCTCTCGAATCCAAGAGAACTTCGCCACATTGGACTATCAAGGTATCAAGAGTGAAGTGATGGATGTGGTTAGTAA
ACACTTCCGCCCAGAGTTCTTGAACCGTGTTGACGAAATAGTGGTATTCCACCCACTTGGTCAAGAGCACATTAAGTCCA
TTGCTTCTATTCAATTAGAACGCTTGGCAAAACGACTAGAAGAAAAAGGGTATCAATTGGAGGTGTCTGATAAAGCACTC
GACTTGATCGCCCAAGTCGGTTTCGACCCAGTATACGGTGCACGTCCTTTAAAACGTGCAATTCAACAGAATGTCGAGAA
CCCATTAGCTAAATCCATTCTTGCTGGTGAAATAGTTCCAGACAAGAAAGTGCAGCTAATCGTTACTAATGACCAAATTC
TCGCTCATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-320)

3D structure

• AlphaFold DB: Q87S63

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.597	100	0.471
clpE	Streptococcus mutans UA159	49.115	79.113	0.389
clpE	Streptococcus pneumoniae Rx1	47.701	81.214	0.387
clpE	Streptococcus pneumoniae D39	47.701	81.214	0.387
clpE	Streptococcus pneumoniae R6	47.701	81.214	0.387
clpC	Lactococcus lactis subsp. cremoris KW2	46.965	80.747	0.379