Detailed information NTG0288134

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: DBZ62_RS25255
• Genome accession: NZ_CP028849
• Coordinates: 5284179..5285516 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain IMP68
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5279179..5290516

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DBZ62_RS25230 (DBZ62_25160)	pgeF	5279322..5280050 (-)	729	WP_003123393.1	peptidoglycan editing factor PgeF	-
DBZ62_RS25235 (DBZ62_25165)	rluD	5280047..5281009 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
DBZ62_RS25240 (DBZ62_25170)	-	5281155..5282180 (+)	1026	WP_023092932.1	outer membrane protein assembly factor BamD	-
DBZ62_RS25245 (DBZ62_25175)	-	5282337..5282582 (+)	246	WP_003102591.1	PP0621 family protein	-
DBZ62_RS25250 (DBZ62_25180)	pilS	5282572..5284164 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
DBZ62_RS25255 (DBZ62_25185)	pilR	5284179..5285516 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
DBZ62_RS25260 (DBZ62_25190)	thiO	5285562..5286656 (-)	1095	WP_023518092.1	glycine oxidase ThiO	-
DBZ62_RS25265 (DBZ62_25195)	-	5286791..5287300 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
DBZ62_RS25270 (DBZ62_25200)	-	5287406..5287912 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
DBZ62_RS25275 (DBZ62_25205)	pilV	5287903..5288460 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
DBZ62_RS25280 (DBZ62_25210)	pilW	5288457..5289281 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
DBZ62_RS25285 (DBZ62_25215)	pilX	5289278..5289865 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=288134 DBZ62_RS25255 WP_003094694.1 5284179..5285516(+) (pilR) [Pseudomonas aeruginosa strain IMP68]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=288134 DBZ62_RS25255 WP_003094694.1 5284179..5285516(+) (pilR) [Pseudomonas aeruginosa strain IMP68]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384