Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EGM66_RS27485 Genome accession   NZ_CP033884
Coordinates   5130793..5131449 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 50579417     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5125793..5136449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGM66_RS27455 (EGM66_27480) yecA 5127044..5127709 (-) 666 WP_000847881.1 UPF0149 family protein YecA -
  EGM66_RS27475 (EGM66_27500) pgsA 5128359..5128907 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EGM66_RS27480 (EGM66_27505) uvrC 5128964..5130796 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EGM66_RS27485 (EGM66_27510) letA 5130793..5131449 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EGM66_RS27490 (EGM66_27515) yecU 5131745..5131921 (+) 177 WP_000590347.1 protein YecU -
  EGM66_RS27495 (EGM66_27520) yecF 5131908..5132132 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EGM66_RS27500 (EGM66_27525) sdiA 5132199..5132921 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  EGM66_RS27505 (EGM66_27530) tcyN 5133151..5133903 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EGM66_RS27510 (EGM66_27535) tcyL 5133900..5134568 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EGM66_RS27515 (EGM66_27540) dcyD 5134583..5135569 (-) 987 WP_020232905.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=285774 EGM66_RS27485 WP_000611328.1 5130793..5131449(-) (letA) [Escherichia coli strain 50579417]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=285774 EGM66_RS27485 WP_000611328.1 5130793..5131449(-) (letA) [Escherichia coli strain 50579417]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482