Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EGY17_RS23780 Genome accession   NZ_CP033850
Coordinates   4485321..4485977 (-) Length   218 a.a.
NCBI ID   WP_022645829.1    Uniprot ID   -
Organism   Escherichia coli strain FDAARGOS_497     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4480321..4490977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGY17_RS23745 (EGY17_23775) - 4480387..4481475 (-) 1089 Protein_4271 IS3 family transposase -
  EGY17_RS23750 (EGY17_23780) - 4481537..4482189 (+) 653 Protein_4272 hypothetical protein -
  EGY17_RS23770 (EGY17_23800) pgsA 4482887..4483435 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EGY17_RS23775 (EGY17_23805) uvrC 4483492..4485324 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EGY17_RS23780 (EGY17_23810) letA 4485321..4485977 (-) 657 WP_022645829.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EGY17_RS23785 (EGY17_23815) yecU 4486273..4486449 (+) 177 WP_001307856.1 protein YecU -
  EGY17_RS23790 (EGY17_23820) yecF 4486436..4486660 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EGY17_RS23795 (EGY17_23825) sdiA 4486727..4487449 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  EGY17_RS23800 (EGY17_23830) tcyN 4487679..4488431 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EGY17_RS23805 (EGY17_23835) tcyL 4488428..4489096 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EGY17_RS23810 (EGY17_23840) dcyD 4489111..4490097 (-) 987 WP_001128235.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23938.73 Da        Isoelectric Point: 6.9612

>NTDB_id=285446 EGY17_RS23780 WP_022645829.1 4485321..4485977(-) (letA) [Escherichia coli strain FDAARGOS_497]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIAYDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=285446 EGY17_RS23780 WP_022645829.1 4485321..4485977(-) (letA) [Escherichia coli strain FDAARGOS_497]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTATGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482