Detailed information NTG0285221

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: C5Y81_RS13810
• Genome accession: NZ_CP028470
• Coordinates: 2672437..2673324 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IT4-R
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2667437..2678324

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C5Y81_RS13775 (C5Y81_13775)	-	2667455..2667543 (+)	89	Protein_2572	hypothetical protein	-
C5Y81_RS13780 (C5Y81_13780)	-	2667651..2668148 (-)	498	WP_001065267.1	glutathione peroxidase	-
C5Y81_RS13785 (C5Y81_13785)	-	2668158..2668418 (-)	261	WP_072434822.1	hypothetical protein	-
C5Y81_RS13795 (C5Y81_13795)	-	2668800..2668913 (-)	114	WP_072384844.1	hypothetical protein	-
C5Y81_RS13800 (C5Y81_13800)	-	2669577..2671577 (-)	2001	WP_000776746.1	ABC transporter permease	-
C5Y81_RS13805 (C5Y81_13805)	-	2671574..2672329 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
C5Y81_RS13810 (C5Y81_13810)	braS	2672437..2673324 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
C5Y81_RS13815 (C5Y81_13815)	braR	2673335..2674000 (-)	666	WP_052997578.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
C5Y81_RS13820 (C5Y81_13820)	-	2674026..2674226 (-)	201	WP_000604723.1	hypothetical protein	-
C5Y81_RS13825 (C5Y81_13825)	-	2674424..2675848 (+)	1425	WP_000953731.1	alkaline phosphatase	-
C5Y81_RS14510	-	2675918..2676028 (+)	111	WP_001791296.1	hypothetical protein	-
C5Y81_RS13835 (C5Y81_13835)	-	2676131..2676586 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
C5Y81_RS13840 (C5Y81_13840)	-	2676832..2677593 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=285221 C5Y81_RS13810 WP_000143420.1 2672437..2673324(-) (braS) [Staphylococcus aureus strain IT4-R]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=285221 C5Y81_RS13810 WP_000143420.1 2672437..2673324(-) (braS) [Staphylococcus aureus strain IT4-R]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993