Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EGX82_RS10325 Genome accession   NZ_CP033822
Coordinates   1968620..1970401 (+) Length   593 a.a.
NCBI ID   WP_001003953.1    Uniprot ID   Q8CX26
Organism   Streptococcus agalactiae strain FDAARGOS_512     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1963620..1975401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX82_RS10300 (EGX82_10300) - 1964460..1965056 (-) 597 WP_000162275.1 Ltp family lipoprotein -
  EGX82_RS10305 (EGX82_10305) - 1965278..1965775 (+) 498 WP_000582587.1 hypothetical protein -
  EGX82_RS10310 (EGX82_10310) - 1965779..1966195 (+) 417 WP_000245057.1 VOC family protein -
  EGX82_RS10315 (EGX82_10315) - 1966295..1967635 (+) 1341 WP_000285046.1 MATE family efflux transporter -
  EGX82_RS10320 (EGX82_10320) - 1967694..1968461 (-) 768 WP_000567585.1 epoxyqueuosine reductase QueH -
  EGX82_RS10325 (EGX82_10325) uvrC 1968620..1970401 (+) 1782 WP_001003953.1 excinuclease ABC subunit UvrC Machinery gene
  EGX82_RS10330 (EGX82_10330) - 1970443..1972224 (-) 1782 WP_000942620.1 glycerophosphodiester phosphodiesterase -
  EGX82_RS10335 (EGX82_10335) - 1972394..1972995 (+) 602 Protein_1898 nitroreductase family protein -
  EGX82_RS10340 (EGX82_10340) pepV 1973042..1974448 (+) 1407 WP_000150956.1 dipeptidase PepV -
  EGX82_RS10345 (EGX82_10345) - 1974545..1975129 (+) 585 WP_123922137.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68357.90 Da        Isoelectric Point: 9.5330

>NTDB_id=284959 EGX82_RS10325 WP_001003953.1 1968620..1970401(+) (uvrC) [Streptococcus agalactiae strain FDAARGOS_512]
MNELIKHKLELLPDSPGCYLHKDKNGTIIYVGKAKNLKNRVKSYFHGSHNTKTELLVSEIEDFEYIVTTSNTEALLLEIN
LIQENMPKYNIRLKDDKSYPYIKITNERYPRLMITRQVKKSDGTYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCNAHTVCQTNKAYWDSLREDVKQFLNGKDNKIVNGLTEKMKSAAMTMEFERAAEYRDLIEAISLLRTKQRVIHQ
DMKDRDVFGYFVDKGWMCVQVFFVRNGKLIQRDVNMFPYYNEPEEDFLTYIGQFYQDTKHFLPKEVFIPQDIDAKSVETI
VGCKIVKPQRGEKKQLVNLAIKNARVSLQQKFDLLEKDIRKTHGAIENLGNLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVNGKPSKKDYRKFKIKTVIGPDDYASMREVIHRRYSRVLKDGLTPPDLIVIDGGQGQVNIARDVIENQLGLAIPIAGLQ
KNDKHQTHELLFGDPLEVVELPRNSEEFFLLHRIQDEVHRFAITFHRQLRSKNSFSSKLDGITGLGPKRKQLLMKHFKSL
PNIQKAEIEDIIMCGIPRTVAESLRDSLNDPPK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=284959 EGX82_RS10325 WP_001003953.1 1968620..1970401(+) (uvrC) [Streptococcus agalactiae strain FDAARGOS_512]
ATGAATGAACTGATTAAACATAAGCTAGAATTGTTACCAGACAGTCCTGGTTGTTACCTTCATAAAGATAAGAATGGGAC
AATTATTTATGTAGGTAAGGCTAAAAATCTTAAGAATCGTGTGAAAAGTTATTTTCATGGGAGTCATAATACTAAGACAG
AACTTTTGGTCTCTGAGATTGAAGACTTTGAATACATTGTGACAACATCTAATACCGAAGCTCTATTATTGGAAATTAAT
TTAATCCAAGAAAATATGCCGAAGTATAATATTCGATTGAAAGATGATAAGTCTTACCCATATATCAAAATAACAAATGA
ACGTTATCCTCGTCTTATGATTACACGTCAAGTAAAAAAATCAGATGGCACTTATTTTGGACCTTATCCGGATTCTGGGG
CAGCAACTGAGATTAAGCGGTTACTAGATAGGCTCTTTCCTTTTAAGAAATGTACTAATCCAGCAAATAAAGTATGCTTT
TATTATCATTTAGGGCAATGCAATGCACATACAGTTTGTCAAACTAATAAAGCTTATTGGGATAGTCTGAGAGAAGATGT
AAAACAGTTTCTTAATGGTAAAGATAATAAAATTGTTAACGGATTAACTGAAAAAATGAAGAGCGCTGCTATGACTATGG
AATTTGAGCGTGCGGCTGAATATCGAGATTTGATCGAAGCAATTAGTTTGTTGCGTACTAAGCAGCGTGTTATTCATCAA
GATATGAAGGATAGAGATGTTTTTGGTTATTTCGTTGATAAGGGTTGGATGTGTGTACAGGTCTTTTTTGTTCGAAATGG
AAAATTGATTCAGCGTGACGTGAATATGTTTCCTTATTATAATGAACCAGAGGAAGATTTTCTAACTTACATAGGGCAAT
TTTATCAAGATACAAAACATTTTCTACCCAAAGAAGTCTTTATTCCACAGGATATTGATGCTAAGTCGGTTGAAACAATT
GTAGGCTGTAAGATTGTTAAACCACAACGTGGTGAAAAGAAACAGTTAGTAAATCTGGCAATAAAAAATGCTCGTGTCAG
TTTACAACAGAAGTTTGACTTACTGGAAAAAGATATTCGTAAAACTCATGGGGCAATTGAAAATTTAGGTAATCTTCTTA
ATATCCCTAAACCAGTACGCATAGAAGCATTTGATAATTCCAATATTCAAGGGACAAGTCCAGTAGCTGCTATGGTGGTA
TTTGTGAATGGAAAGCCAAGTAAAAAAGACTATCGAAAGTTTAAAATTAAGACTGTTATCGGACCAGATGATTATGCTAG
TATGAGAGAAGTCATTCATCGGCGTTATAGTAGGGTTTTAAAAGATGGCTTGACACCTCCGGACTTGATTGTAATTGATG
GTGGTCAGGGGCAAGTAAATATAGCGCGTGATGTTATTGAGAACCAATTAGGTTTAGCCATACCTATTGCAGGTTTGCAA
AAGAATGATAAACACCAAACACATGAATTACTTTTTGGAGATCCTTTAGAAGTAGTAGAATTACCGCGTAATTCAGAAGA
ATTTTTCTTACTTCACCGTATTCAAGATGAGGTACATCGTTTTGCTATTACTTTTCATCGTCAATTACGCTCCAAAAATT
CCTTTTCTTCAAAATTAGATGGTATCACTGGGTTGGGACCAAAACGTAAACAATTGCTAATGAAACATTTTAAAAGCTTA
CCTAATATCCAAAAAGCTGAGATTGAGGACATTATTATGTGTGGTATTCCTAGGACTGTTGCAGAAAGTCTCCGAGATTC
TCTTAATGATCCTCCTAAATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8CX26

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.57

99.325

0.761
  uvrC Streptococcus pneumoniae R6

76.231

99.325

0.757
  uvrC Streptococcus pneumoniae D39

76.231

99.325

0.757