Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   EGX80_RS05645 Genome accession   NZ_CP033815
Coordinates   1043863..1044147 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain FDAARGOS_514     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1038863..1049147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX80_RS05620 (EGX80_05630) - 1040809..1041174 (+) 366 WP_002986560.1 DUF1033 family protein -
  EGX80_RS05625 (EGX80_05635) comGA 1041267..1042205 (+) 939 WP_011054114.1 competence type IV pilus ATPase ComGA Machinery gene
  EGX80_RS05630 (EGX80_05640) comGB 1042141..1043175 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  EGX80_RS05635 (EGX80_05645) comGC 1043177..1043503 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  EGX80_RS05640 (EGX80_05650) comGD 1043478..1043906 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  EGX80_RS05645 (EGX80_05655) comGE 1043863..1044147 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  EGX80_RS05650 (EGX80_05660) comGF 1044140..1044574 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  EGX80_RS05655 (EGX80_05665) comGG 1044558..1044884 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  EGX80_RS05660 (EGX80_05670) comGH 1044982..1045935 (+) 954 WP_011054117.1 class I SAM-dependent methyltransferase Machinery gene
  EGX80_RS05665 (EGX80_05675) - 1045994..1047190 (+) 1197 WP_010921803.1 acetate kinase -
  EGX80_RS05670 (EGX80_05680) - 1047376..1047684 (+) 309 WP_011054118.1 hypothetical protein -
  EGX80_RS05675 (EGX80_05685) proC 1047767..1048537 (-) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=284817 EGX80_RS05645 WP_002987779.1 1043863..1044147(+) (comGE) [Streptococcus pyogenes strain FDAARGOS_514]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=284817 EGX80_RS05645 WP_002987779.1 1043863..1044147(+) (comGE) [Streptococcus pyogenes strain FDAARGOS_514]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTGAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383