Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SK637_RS08035 Genome accession   NZ_CP028415
Coordinates   1608261..1608950 (-) Length   229 a.a.
NCBI ID   WP_033689345.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1603261..1613950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS08010 (SK637_01567) - 1604138..1605145 (-) 1008 WP_033689338.1 phosphomevalonate kinase -
  SK637_RS08015 (SK637_01568) mvaD 1605132..1606085 (-) 954 WP_033689340.1 diphosphomevalonate decarboxylase -
  SK637_RS08020 (SK637_01569) mvk 1606067..1606945 (-) 879 WP_033689342.1 mevalonate kinase -
  SK637_RS08030 (SK637_01570) - 1607221..1608162 (-) 942 WP_033689344.1 N-acetylmuramoyl-L-alanine amidase family protein -
  SK637_RS08035 (SK637_01571) covR 1608261..1608950 (-) 690 WP_033689345.1 response regulator transcription factor Regulator
  SK637_RS08040 (SK637_01572) gndA 1608962..1610386 (-) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  SK637_RS08045 (SK637_01573) mapZ 1610462..1611856 (-) 1395 WP_033689347.1 cell division site-positioning protein MapZ -
  SK637_RS08050 (SK637_01574) - 1611869..1613026 (-) 1158 WP_033689348.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  SK637_RS08060 (SK637_01575) gpsB 1613513..1613842 (-) 330 WP_033689349.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26799.93 Da        Isoelectric Point: 8.0259

>NTDB_id=284723 SK637_RS08035 WP_033689345.1 1608261..1608950(-) (covR) [Streptococcus mitis strain SK637]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIENLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=284723 SK637_RS08035 WP_033689345.1 1608261..1608950(-) (covR) [Streptococcus mitis strain SK637]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCGTCTGGGGGATATGACTGCCCAGGATTTTGCAGACAAGCTGAGTCGGACTAAGCCAGCCTCAGTCATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGATCAGATTGAAACAATCCAACGCTTTGCCGTCTCTTACATTTATAAGCCAGTTATTAT
TGAGAATCTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGATCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACAGTTTATCGTGGCGAGGAAATGATTGCTCTGACGCGC
CGTGAGTATGATCTTTTGGCTACTCTTATGGGAAGCAAGAAAGTCCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACCAATATCGTGGATGTCTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment