Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   SM12261_RS04420 Genome accession   NZ_CP028414
Coordinates   819626..821428 (+) Length   600 a.a.
NCBI ID   WP_000244089.1    Uniprot ID   A0A081SCJ2
Organism   Streptococcus mitis NCTC 12261     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 814626..826428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS04400 (SM12261_0854) rnr 814922..817276 (+) 2355 WP_000654876.1 ribonuclease R -
  SM12261_RS04405 (SM12261_0855) smpB 817239..817706 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  SM12261_RS04410 (SM12261_0856) tehB 817721..818581 (+) 861 WP_000413782.1 SAM-dependent methyltransferase TehB -
  SM12261_RS04415 (SM12261_0857) coiA 818654..819607 (+) 954 WP_000495920.1 competence protein CoiA Machinery gene
  SM12261_RS04420 (SM12261_0858) pepF 819626..821428 (+) 1803 WP_000244089.1 oligoendopeptidase F Regulator
  SM12261_RS04425 (SM12261_0859) - 821430..822143 (+) 714 WP_004239376.1 O-methyltransferase -
  SM12261_RS04430 (SM12261_0860) prsA 822210..823148 (+) 939 WP_000727954.1 peptidylprolyl isomerase PrsA -
  SM12261_RS04435 (SM12261_0861) ftsW 823309..824532 (+) 1224 WP_000703370.1 cell division peptidoglycan polymerase FtsW -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69921.80 Da        Isoelectric Point: 4.5649

>NTDB_id=284641 SM12261_RS04420 WP_000244089.1 819626..821428(+) (pepF) [Streptococcus mitis NCTC 12261]
MVLQRHEINEKDTWDLSTIYPTDQAWEEALKDITEQLETVAQYEGHLLDSADSLLEITEFSLEMERQMEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEEQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKNREVRRGAYQALYATYQQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLNLRSKILGISDLKMYDVYTPLSSVEYSFTYREALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGNQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGMA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=284641 SM12261_RS04420 WP_000244089.1 819626..821428(+) (pepF) [Streptococcus mitis NCTC 12261]
ATGGTATTACAAAGACATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATATAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCCTGGATAGTGCGGATAGTC
TACTCGAAATTACTGAATTTTCTCTTGAAATGGAACGCCAAATGGAGAAGCTTTACGTTTATGCTCATATGAAGAATGAC
CAAGACACACGTGAAGCCAAGTACCAAGAGTACTATGCCAAGGCCATGACTCTCTATAGCCAGCTAGACCAAGCCTTTTC
ATTCTATGAACCTGAATTTATGGAGATTAGTGAAGAGCAGTATGCTGACTTTTTAGAAGCTCAGCCAAAATTGCAGGTTT
ATCAACACTATTTTGACAAGCTTTTGCAAGGCAAGGATCACGTTCTTTCACAACGCGAAGAAGAATTATTGGCTGGAGCT
GGGGAAATCTTTGGTTCGGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGTTCTTGACGA
TGATGGTAAGGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAATCGTGAGGTTCGTCGTGGTG
CCTATCAAGCCCTTTATGCGACTTATCAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTGCAA
AACTACCGTGCCAAAGTTCGCAACTACAAGAGCGCTCGTCATGCAGCCCTAGCAGCCAATTTTGTTCCAGAGAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTGCATCGCTATCTTAACCTTCGTTCAAAAATCCTGGGAA
TTTCAGACCTCAAGATGTACGATGTCTACACACCACTTTCTTCTGTTGAATACAGTTTTACCTACCGAGAAGCCTTGAAA
AAGGCAGAAGATGCCTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTCAAACGTGCCTTCAGCGAGCGTTGGATTGA
TGTTTACGAAAACCAAGGCAAGCGTTCAGGTGCTTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGCTACTTAATT
GGCAGGACAATTTAGACAATCTCTTTACCCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACTCGTGAAACG
CAGCCTTATGTTTACGGAGATTATTCTATCTTCTTGGCTGAGATTGCATCAACTACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGATGATGCAACGCGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGGACAGTTT
TCCGTCAAACTCAATTTGCTGAGTTTGAACACGCGATTCACCAAGCGGACCAAAATGGAGAAGTCTTGACAAGTGATTTC
CTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCTCGCATTCCACACTTCTACTATAACTACTATGTATACCAATATTCAACTGGCTTTGCAGCAGCCTCAGCCTTGGCTG
AAAAGATTGTCCATGGTAATCAAGAAGACCGTGACCGCTATATCGACTATCTCAAGGCAGGTAAGTCTGACTATCCACTT
AATGTCATGAGAAAAGCTGGAGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGAACGTCGTTT
AAATGAGTTTGAAGCACTTGTTGAAAAATTGGGAATGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A081SCJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

66.946

99.333

0.665

Multiple sequence alignment