Detailed information NTG0284629

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: SM12261_RS01755
• Genome accession: NZ_CP028414
• Coordinates: 331475..332206 (+)
• Length: 243 a.a.
• NCBI ID: WP_000889948.1
• Uniprot ID: A0AAX2LG84
• Organism: Streptococcus mitis NCTC 12261
• Function: export ComS (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	328452..339716	331475..332206	within	0

Gene organization within MGE regions

Location: 328452..339716

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SM12261_RS01735 (SM12261_0336)	-	328452..329084 (+)	633	WP_000756346.1	DJ-1/PfpI family protein	-
SM12261_RS01740 (SM12261_0337)	dnaJ	329283..330419 (+)	1137	WP_001066310.1	molecular chaperone DnaJ	-
SM12261_RS01745 (SM12261_0338)	-	330700..330987 (-)	288	WP_000777752.1	hypothetical protein	-
SM12261_RS01750 (SM12261_0339)	-	330997..331407 (-)	411	WP_001278319.1	HIT family protein	-
SM12261_RS01755 (SM12261_0340)	pptA	331475..332206 (+)	732	WP_000889948.1	ABC transporter ATP-binding protein	Regulator
SM12261_RS01760 (SM12261_0341)	-	332203..333252 (+)	1050	WP_000653760.1	ABC transporter permease	-
SM12261_RS01765 (SM12261_0342)	-	333314..333643 (-)	330	WP_000132585.1	hypothetical protein	-
SM12261_RS01770 (SM12261_0343)	comE/blpR	333939..334685 (+)	747	WP_001219140.1	response regulator transcription factor	Regulator
SM12261_RS01775 (SM12261_0344)	-	334690..336039 (+)	1350	WP_000409121.1	sensor histidine kinase	-
SM12261_RS01795 (SM12261_0346)	-	337347..337751 (+)	405	WP_000846948.1	hypothetical protein	-
SM12261_RS01800 (SM12261_0347)	-	337772..337999 (+)	228	WP_001093254.1	bacteriocin class II family protein	-
SM12261_RS01805 (SM12261_0348)	-	338014..338334 (+)	321	WP_000645118.1	hypothetical protein	-
SM12261_RS01810 (SM12261_0349)	-	338363..338767 (+)	405	WP_000717993.1	hypothetical protein	-
SM12261_RS01815 (SM12261_0350)	blpZ	338826..339074 (+)	249	WP_000276515.1	immunity protein BlpZ	-
SM12261_RS01820 (SM12261_0351)	-	339105..339716 (+)	612	WP_000394026.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 27161.65 Da
• Isoelectric Point: 5.0011

>NTDB_id=284629 SM12261_RS01755 WP_000889948.1 331475..332206(+) (pptA) [Streptococcus mitis NCTC 12261]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLTPYSGSININGLTLQEDATNYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAIADLIQLLKVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAHGNLQQLREAFNMPEASLNDIYLALTKE
EEL

Nucleotide

• Length: 732 bp

>NTDB_id=284629 SM12261_RS01755 WP_000889948.1 331475..332206(+) (pptA) [Streptococcus mitis NCTC 12261]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTCCATGTCCCTGTCTTGAAAGATGTGTCCTTTACAGTTGAAAGTGG
GCAGTTAGTCGGTTTGATCGGTCTCAATGGTGCTGGGAAATCGACGACCATCAATGAAATTATCGGTCTGTTGACACCTT
ATAGCGGATCTATCAATATCAATGGCTTGACCCTGCAAGAAGATGCGACCAACTACCGCAAACAGATTGGTTACATTCCT
GAGACACCCAGTCTGTATGAGGAATTAACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTATGGTATCGAGCAAAA
AGTGGCTTTTGAACGAGTAGAACCCTTGTTAAAAATGTTTCGTCTGGACCAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTTATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTCTTTATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTGGCGATTGCGGACTTGATTCAGCTTTTGAAAGTGGAAAAGCAAAAGGGCAAGTCCATTCTCAT
GAGTACCCACGTTCTGGATTCGGCGGAGAAGATGTGTGATGCCTTTGTCATTCTCCACAAGGGGGAGGTGCGTGCTCATG
GGAACCTCCAGCAACTCCGCGAAGCCTTTAACATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACCAAAGAG
GAGGAGTTATGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.199	99.177	0.716
pptA	Streptococcus thermophilus LMD-9	71.369	99.177	0.708