Detailed information NTG0284580

Bioinformatically predicted

Overview

• Name: pepF
• Type: Regulator
• Locus tag: C9I44_RS08135
• Genome accession: NZ_CP028386
• Coordinates: 1590109..1591914 (-)
• Length: 601 a.a.
• NCBI ID: WP_003132689.1
• Uniprot ID: G0WJR1
• Organism: Lactococcus garvieae strain IBB3403
• Function: degradation of XIP; competence shut-off (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1589468..1593406	1590109..1591914	within	0

Gene organization within MGE regions

Location: 1589468..1593406

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C9I44_RS08125	-	1589468..1590000 (+)	533	Protein_1607	transposase	-
C9I44_RS08130 (C9I44_08095)	-	1589987..1590106 (-)	120	Protein_1608	O-methyltransferase	-
C9I44_RS08135 (C9I44_08100)	pepF	1590109..1591914 (-)	1806	WP_003132689.1	oligoendopeptidase F	Regulator
C9I44_RS08140 (C9I44_08105)	coiA	1591977..1592624 (-)	648	WP_023189914.1	competence protein CoiA family protein	Machinery gene
C9I44_RS08145 (C9I44_08110)	-	1592855..1593406 (+)	552	WP_011997527.1	recombinase family protein	-

Sequence

Protein

• Length: 601 a.a.
• Molecular weight: 69907.89 Da
• Isoelectric Point: 5.0564

>NTDB_id=284580 C9I44_RS08135 WP_003132689.1 1590109..1591914(-) (pepF) [Lactococcus garvieae strain IBB3403]
MAKNRNEIPEKLTWDLTTIYKTDKEWEAELTRIKSELSLVEETDPGHLLDSAESLLTITEKMLSISQQVEKLYVYASMKN
DQDTREAKYQEYQSKATALYVKFGEVYAFYEPEFLKISKEVYNKWLGELQKLKNYDHMFERLFAKKAHILSQKEEKLLAA
AGEIFESPSETFEIFDNADIKLPMVKNESDEMIQLTHGNYSSLMESKNRGVRKAAYKALYSNYEQYQHTYAKTLQTNVKV
HNLKAQIRSYDSARQAALANNFVPEKVYDVLMEAIHQHLPLLHRYIELRKKILGITDLKMYDIYTPLSNLDYKFNYEDGV
KKAEEVLAIFGKEYKGKVKAAFEQRWIDVEENIGKRSGAYSGGSYDTNAFMLLNWQETLDDLFTLVHEMGHSMHSAFTRE
NQPYVYGDYPIFLAEIASTTNENILTETLLKESKDDKERFALLNHWLDSFRGTVFRQSQFAEFEQKIHEADAAGEVLTSE
YLNSLYGEINEKYYNLAVKENPEIQYEWARIPHFYYNFYVFQYATGFAAATFLAEKVVHGSTEDRQKYLEYLKAGSSAYP
LEVIAKAGVDMESTDYLDAAFELFENRLSELEKLVEKGVHL

Nucleotide

• Length: 1806 bp

>NTDB_id=284580 C9I44_RS08135 WP_003132689.1 1590109..1591914(-) (pepF) [Lactococcus garvieae strain IBB3403]
ATGGCTAAGAACAGAAATGAAATTCCTGAAAAATTAACTTGGGATTTGACAACAATTTATAAAACAGATAAAGAATGGGA
AGCAGAGCTAACTAGAATAAAAAGCGAACTTTCACTCGTTGAAGAGACAGACCCTGGTCATTTACTTGATTCAGCTGAAA
GTCTTCTGACAATTACCGAAAAAATGCTATCCATTTCTCAACAAGTTGAAAAACTATATGTTTATGCTTCTATGAAAAAT
GATCAAGATACCAGAGAGGCTAAATATCAGGAGTATCAATCAAAAGCAACAGCCCTCTATGTGAAATTCGGAGAGGTCTA
TGCCTTCTATGAACCTGAATTTTTGAAAATTTCAAAAGAAGTTTATAACAAATGGTTGGGGGAGCTTCAAAAATTAAAAA
ACTATGACCATATGTTTGAGCGCCTTTTTGCAAAAAAAGCGCATATTCTTAGTCAAAAAGAGGAAAAGTTATTGGCTGCG
GCTGGTGAAATTTTTGAAAGTCCTTCAGAAACTTTTGAAATTTTTGATAATGCGGATATTAAGTTACCTATGGTCAAAAA
TGAATCTGATGAGATGATTCAACTCACGCATGGAAATTACTCTTCCTTAATGGAAAGTAAGAATAGGGGAGTACGAAAAG
CAGCCTACAAAGCACTTTATAGTAATTATGAACAATATCAGCATACTTATGCAAAGACCTTACAGACTAATGTAAAAGTC
CATAATCTTAAAGCCCAAATCCGCTCTTATGATTCAGCCCGTCAAGCTGCTCTGGCTAATAATTTTGTTCCAGAAAAAGT
TTACGATGTTTTGATGGAGGCCATTCATCAACATTTGCCACTTTTACATCGTTATATTGAACTACGCAAGAAAATTTTAG
GAATTACTGATTTAAAGATGTATGATATCTATACTCCATTATCTAATTTAGATTATAAATTTAACTATGAAGATGGAGTG
AAAAAAGCAGAAGAAGTTTTAGCGATATTTGGTAAAGAATATAAAGGAAAAGTTAAAGCAGCTTTTGAACAAAGATGGAT
TGATGTCGAAGAAAATATCGGAAAACGTTCGGGTGCTTATTCAGGTGGATCTTATGATACCAATGCTTTTATGCTTCTAA
ATTGGCAAGAAACGTTAGATGATCTTTTTACTTTAGTTCATGAAATGGGGCACTCAATGCATAGTGCTTTCACGCGTGAA
AACCAACCATATGTTTATGGGGATTATCCAATCTTTTTAGCTGAAATTGCCTCAACTACAAATGAAAATATTTTAACTGA
AACTTTATTAAAGGAAAGTAAAGATGATAAGGAGCGCTTCGCCCTTTTGAACCACTGGCTTGATAGTTTCCGTGGAACTG
TTTTCCGTCAGAGTCAATTTGCCGAATTTGAACAAAAAATTCATGAAGCAGATGCTGCCGGTGAAGTTTTAACAAGTGAA
TACTTAAACTCACTTTATGGCGAAATAAATGAAAAATACTATAATTTAGCAGTCAAAGAAAATCCAGAAATTCAGTATGA
ATGGGCTAGAATTCCGCATTTTTATTATAATTTCTATGTTTTTCAATACGCAACAGGTTTTGCTGCGGCAACTTTCTTAG
CTGAAAAAGTTGTTCATGGTTCAACTGAGGATCGTCAAAAATATCTTGAATATTTGAAGGCAGGTTCCTCAGCTTATCCT
TTAGAAGTAATTGCCAAAGCTGGAGTTGATATGGAATCTACCGATTATTTAGATGCTGCCTTTGAGCTTTTTGAAAATCG
ATTGAGTGAATTAGAAAAATTAGTTGAAAAAGGAGTCCATCTTTAA

Domains

Predicted by InterproScan.

• Oligopeptidase F (Peptidase_M3_N) (113-181)

• Peptidase family M3 (Peptidase_M3) (203-582)

3D structure

• AlphaFold DB: G0WJR1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pepF	Streptococcus salivarius strain HSISS4	64.06	100	0.641