Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CQP61_RS16925 Genome accession   NZ_CP033635
Coordinates   2856766..2857422 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli isolate ECCNB12-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2851766..2862422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CQP61_RS16895 (CQP61_16880) yecA 2853017..2853682 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  CQP61_RS16915 (CQP61_16900) pgsA 2854332..2854880 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CQP61_RS16920 (CQP61_16905) uvrC 2854937..2856769 (-) 1833 WP_121831921.1 excinuclease ABC subunit UvrC Machinery gene
  CQP61_RS16925 (CQP61_16910) letA 2856766..2857422 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CQP61_RS32695 - 2857564..2857635 (+) 72 Protein_2803 transcriptional regulator -
  CQP61_RS16930 (CQP61_16915) yecU 2857718..2857894 (+) 177 WP_000590347.1 protein YecU -
  CQP61_RS16935 (CQP61_16920) yecF 2857881..2858105 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  CQP61_RS16940 (CQP61_16925) sdiA 2858172..2858894 (-) 723 WP_001154279.1 transcriptional regulator SdiA -
  CQP61_RS16945 (CQP61_16930) tcyN 2859124..2859876 (-) 753 WP_001273007.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CQP61_RS16950 (CQP61_16935) tcyL 2859873..2860541 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  CQP61_RS16955 (CQP61_16940) dcyD 2860556..2861542 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=284036 CQP61_RS16925 WP_000611335.1 2856766..2857422(-) (letA) [Escherichia coli isolate ECCNB12-2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=284036 CQP61_RS16925 WP_000611335.1 2856766..2857422(-) (letA) [Escherichia coli isolate ECCNB12-2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486