Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EGC57_RS07390 Genome accession   NZ_CP033621
Coordinates   1432117..1432899 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain M75     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1427117..1437899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGC57_RS07360 (EGC57_07370) gatB 1427215..1428654 (-) 1440 WP_011054945.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  EGC57_RS07365 (EGC57_07375) gatA 1428654..1430120 (-) 1467 WP_076639439.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  EGC57_RS07370 (EGC57_07380) gatC 1430120..1430422 (-) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  EGC57_RS07375 (EGC57_07385) - 1430654..1430939 (-) 286 Protein_1372 putative PEP-binding protein -
  EGC57_RS07385 (EGC57_07395) - 1431416..1431970 (-) 555 WP_002983281.1 isochorismatase family cysteine hydrolase -
  EGC57_RS07390 (EGC57_07400) codY 1432117..1432899 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EGC57_RS07395 (EGC57_07405) - 1433117..1434331 (-) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  EGC57_RS07400 (EGC57_07410) - 1434562..1435014 (+) 453 WP_002992571.1 universal stress protein -
  EGC57_RS07405 (EGC57_07415) - 1435137..1436525 (-) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  EGC57_RS07410 (EGC57_07420) - 1436597..1437562 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=283969 EGC57_RS07390 WP_002983278.1 1432117..1432899(-) (codY) [Streptococcus pyogenes strain M75]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=283969 EGC57_RS07390 WP_002983278.1 1432117..1432899(-) (codY) [Streptococcus pyogenes strain M75]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment