Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D8668_RS31140 Genome accession   NZ_CP033439
Coordinates   6594401..6595024 (+) Length   207 a.a.
NCBI ID   WP_003111192.1    Uniprot ID   A0A0H2ZJZ4
Organism   Pseudomonas aeruginosa strain SP4528     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 6589401..6600024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8668_RS31115 (D8668_31115) - 6590486..6590713 (-) 228 WP_003097347.1 DUF1161 domain-containing protein -
  D8668_RS31120 (D8668_31120) - 6590897..6591112 (-) 216 WP_003097345.1 dodecin -
  D8668_RS31125 (D8668_31125) trpI 6591213..6592100 (-) 888 WP_003111191.1 trpBA operon transcriptional activator TrpI -
  D8668_RS31130 (D8668_31130) trpB 6592204..6593412 (+) 1209 WP_003097340.1 tryptophan synthase subunit beta -
  D8668_RS31135 (D8668_31135) trpA 6593409..6594215 (+) 807 WP_003097337.1 tryptophan synthase subunit alpha -
  D8668_RS31140 (D8668_31140) letA 6594401..6595024 (+) 624 WP_003111192.1 response regulator transcription factor Regulator
  D8668_RS31145 (D8668_31145) - 6595032..6595397 (+) 366 WP_003097330.1 Hpt domain-containing protein -
  D8668_RS31150 (D8668_31150) - 6595376..6595753 (-) 378 WP_003114635.1 DOPA 4,5-dioxygenase family protein -
  D8668_RS31155 (D8668_31155) - 6595764..6596678 (-) 915 WP_003122286.1 LysR family transcriptional regulator -
  D8668_RS31160 (D8668_31160) betC 6596791..6598302 (+) 1512 WP_003097323.1 choline-sulfatase -
  D8668_RS31165 (D8668_31165) - 6598319..6599242 (+) 924 WP_003115797.1 choline ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 22859.66 Da        Isoelectric Point: 10.1491

>NTDB_id=283484 D8668_RS31140 WP_003111192.1 6594401..6595024(+) (letA) [Pseudomonas aeruginosa strain SP4528]
MSKVLIVDDHPAIRLAVRLLFERDGFTIVGEADNGAEALQVARKKSPDLAILDIGIPKIDGLEVIARLKSLKLDTKVLVL
TRQNPAQFAPRCLQAGAMGFVSKRENLSELLLAAKAVLAGYIHFPTGALRSINQQSRDNEARMLESLSDREMTVLQYLAN
GNTNKAIAQQLFLSEKTVSTYKSRIMLKLNAHSLAGLIDFARRHELI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=283484 D8668_RS31140 WP_003111192.1 6594401..6595024(+) (letA) [Pseudomonas aeruginosa strain SP4528]
ATGAGTAAGGTGCTGATCGTCGATGATCATCCCGCTATCCGCCTGGCCGTGCGCTTGCTGTTCGAGCGCGACGGTTTCAC
CATCGTCGGCGAGGCCGACAACGGTGCCGAAGCCCTGCAGGTAGCCCGCAAGAAGTCTCCCGACCTGGCCATCCTGGACA
TCGGCATCCCCAAGATCGACGGTCTCGAAGTGATAGCCCGCCTGAAGTCCCTGAAGCTGGACACCAAGGTCCTGGTCCTG
ACCCGGCAGAATCCGGCGCAGTTCGCCCCGCGATGCCTGCAGGCCGGCGCCATGGGCTTCGTCAGCAAAAGGGAAAACCT
CTCCGAGCTGCTGCTCGCCGCCAAGGCCGTGCTGGCCGGCTACATCCACTTCCCCACCGGGGCGTTGCGCAGCATCAACC
AGCAGAGCCGCGACAACGAGGCCCGCATGCTGGAAAGCCTTTCCGACCGCGAGATGACCGTGCTGCAGTACCTGGCCAAC
GGCAATACCAACAAGGCCATCGCCCAGCAGCTGTTCCTCAGCGAGAAAACCGTGAGCACCTACAAGTCACGCATCATGCT
GAAACTCAACGCCCATTCCCTGGCCGGCCTGATCGATTTCGCCCGCCGCCACGAGCTGATCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Bacterial regulatory proteins, luxR family (GerE)

(145-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZJZ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

35.377

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.377

100

0.362