Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   C7M27_RS12885 Genome accession   NZ_CP028213
Coordinates   2472694..2473350 (-) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain SRCM102749     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2467694..2478350
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M27_RS12860 (C7M27_02542) spxH 2467904..2468803 (+) 900 WP_003245184.1 protease adaptor protein SpxH -
  C7M27_RS12865 (C7M27_02543) - 2469118..2469285 (+) 168 WP_003244944.1 hypothetical protein -
  C7M27_RS12870 (C7M27_02544) pepF 2469323..2471152 (-) 1830 WP_201755714.1 oligoendopeptidase F -
  C7M27_RS12875 (C7M27_02545) coiA 2471382..2472503 (-) 1122 WP_250634842.1 competence protein CoiA Machinery gene
  C7M27_RS12880 - 2472577..2472699 (+) 123 WP_003245684.1 hypothetical protein -
  C7M27_RS12885 (C7M27_02546) mecA 2472694..2473350 (-) 657 WP_003232942.1 adaptor protein MecA Regulator
  C7M27_RS12890 - 2473317..2473457 (-) 141 WP_119122854.1 hypothetical protein -
  C7M27_RS12895 (C7M27_02547) yjbE 2473627..2474283 (+) 657 WP_128740217.1 TerC family protein -
  C7M27_RS12900 (C7M27_02548) spx 2474329..2474724 (-) 396 WP_014476435.1 transcriptional regulator Spx -
  C7M27_RS12905 (C7M27_02549) yjbC 2474905..2475483 (-) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  C7M27_RS12910 (C7M27_02550) yjbB 2475647..2476864 (-) 1218 WP_128740216.1 MFS transporter -
  C7M27_RS12915 (C7M27_02551) oppF 2476971..2477888 (-) 918 WP_003239287.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=283192 C7M27_RS12885 WP_003232942.1 2472694..2473350(-) (mecA) [Bacillus subtilis strain SRCM102749]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=283192 C7M27_RS12885 WP_003232942.1 2472694..2473350(-) (mecA) [Bacillus subtilis strain SRCM102749]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment