Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   D9Y32_RS10790 Genome accession   NZ_CP033218
Coordinates   2117207..2117842 (+) Length   211 a.a.
NCBI ID   WP_003185124.1    Uniprot ID   Q65F45
Organism   Bacillus licheniformis strain TCCC 11148     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2112207..2122842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9Y32_RS10765 (D9Y32_10775) - 2113321..2113707 (+) 387 WP_003185133.1 protein liaI -
  D9Y32_RS10770 (D9Y32_10780) liaH 2113728..2114411 (+) 684 WP_009329563.1 stress responsive protein LiaH -
  D9Y32_RS10775 (D9Y32_10785) - 2114517..2115380 (+) 864 WP_142782402.1 DUF4097 domain-containing protein -
  D9Y32_RS10780 (D9Y32_10790) liaF 2115411..2116142 (+) 732 WP_142782403.1 cell wall-active antibiotics response protein LiaF -
  D9Y32_RS10785 (D9Y32_10795) liaS 2116139..2117203 (+) 1065 WP_003185128.1 two-component system sensor histidine kinase LiaS -
  D9Y32_RS10790 (D9Y32_10800) vraR 2117207..2117842 (+) 636 WP_003185124.1 response regulator transcription factor Regulator
  D9Y32_RS10795 (D9Y32_10805) - 2117879..2118262 (-) 384 WP_003185122.1 hypothetical protein -
  D9Y32_RS10800 (D9Y32_10810) - 2118306..2119427 (-) 1122 WP_142782404.1 Ger(x)C family spore germination protein -
  D9Y32_RS10805 (D9Y32_10815) - 2119424..2120524 (-) 1101 WP_142782405.1 endospore germination permease -
  D9Y32_RS10810 (D9Y32_10820) - 2120493..2121935 (-) 1443 WP_011198277.1 spore germination protein -
  D9Y32_RS10815 (D9Y32_10825) - 2122059..2122226 (+) 168 WP_003185114.1 YvzF family protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23095.83 Da        Isoelectric Point: 5.1797

>NTDB_id=282709 D9Y32_RS10790 WP_003185124.1 2117207..2117842(+) (vraR) [Bacillus licheniformis strain TCCC 11148]
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD

Nucleotide


Download         Length: 636 bp        

>NTDB_id=282709 D9Y32_RS10790 WP_003185124.1 2117207..2117842(+) (vraR) [Bacillus licheniformis strain TCCC 11148]
GTGATTCGAGTATTGTTAATTGATGATCATGAAATGGTGAGAATGGGGCTGGCCGCTTTCCTGGAATCCCAGCCTGATAT
TGAAGTGATTGGGGAGGCATCAGACGGAAAGCGCGGCGTTGAATTGGCGCTTGAAACCAAACCCGACGTGATTTTGATGG
ATCTTGTGATGGAAGGGATGGACGGAATTGAGGCCACGAAACAAATATGCCGGCAGCTTGCCGATCCGAAAATCATCGTT
CTGACGAGCTTCGTTGATGATGACAAGGTCTATCCGGTCATCGAAGCCGGAGCGCTCAGCTATTTGCTGAAAACGTCGAA
AGCGAGTGAAATCGCCGATGCGATCAGGGCTGCGAGCGTCGGAGAACCAAAGCTTGAAGCCAAAGTCGCAGGAAAAGTGT
TGTCCAAGCTGAGACATTCAGCCGGCGAACAGCCCCTTCATCAATCGCTGACAGCAAGAGAATTGGAAATCCTCAAACTT
GTAGCAGAGGGCAAGACAAACAAAGGTATTGCCGAAGAATTATATATCACCATTAAAACAGTTAAAACGCATGTGACGAA
CATCCTTTCCAAGCTTGAAGTCGACGACCGGACACAAGCCGCAATCTACGCCCACCGAAACAAACTTGTCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65F45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.11

99.052

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.389

Multiple sequence alignment