Detailed information NTG0282475

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: C7M18_RS04335
• Genome accession: NZ_CP028204
• Coordinates: 877901..879064 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain SRCM102755
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 872901..884064

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M18_RS04305 (C7M18_00864)	-	873166..873585 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
C7M18_RS04310 (C7M18_00865)	comFC	873659..874348 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
C7M18_RS04315 (C7M18_00866)	-	874354..874638 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
C7M18_RS04320 (C7M18_00867)	comFA	874696..876081 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
C7M18_RS04325 (C7M18_00868)	-	876189..877037 (-)	849	WP_003151387.1	DegV family protein	-
C7M18_RS04330 (C7M18_00869)	degU	877135..877824 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
C7M18_RS04335 (C7M18_00870)	degS	877901..879064 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
C7M18_RS04340 (C7M18_00871)	-	879287..879934 (+)	648	WP_007614107.1	YigZ family protein	-
C7M18_RS04345 (C7M18_00872)	-	879939..881153 (+)	1215	WP_103526592.1	LCP family protein	-
C7M18_RS04350 (C7M18_00873)	-	881252..882328 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
C7M18_RS04355 (C7M18_00874)	tuaH	882461..883657 (-)	1197	WP_128496924.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=282475 C7M18_RS04335 WP_007407484.1 877901..879064(-) (degS) [Bacillus velezensis strain SRCM102755]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=282475 C7M18_RS04335 WP_007407484.1 877901..879064(-) (degS) [Bacillus velezensis strain SRCM102755]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951