Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EAF06_RS02045 Genome accession   NZ_CP033158
Coordinates   418964..419620 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CM IVRI KOL-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 413964..424620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EAF06_RS02015 (EAF06_02075) yecA 415217..415882 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  EAF06_RS02035 (EAF06_02095) pgsA 416531..417079 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EAF06_RS02040 (EAF06_02100) uvrC 417136..418967 (-) 1832 Protein_405 excinuclease ABC subunit UvrC -
  EAF06_RS02045 (EAF06_02105) letA 418964..419620 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EAF06_RS25665 (EAF06_02110) - 419762..419878 (+) 117 WP_001302039.1 hypothetical protein -
  EAF06_RS02050 yecU 419916..420092 (+) 177 WP_000590344.1 protein YecU -
  EAF06_RS02055 (EAF06_02115) yecF 420079..420303 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EAF06_RS02060 (EAF06_02120) sdiA 420371..421093 (-) 723 WP_001154260.1 transcriptional regulator SdiA -
  EAF06_RS02065 (EAF06_02125) tcyN 421323..422075 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EAF06_RS02070 (EAF06_02130) tcyL 422072..422740 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EAF06_RS02075 (EAF06_02135) dcyD 422755..423741 (-) 987 WP_039023114.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=282413 EAF06_RS02045 WP_000611328.1 418964..419620(-) (letA) [Escherichia coli strain CM IVRI KOL-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=282413 EAF06_RS02045 WP_000611328.1 418964..419620(-) (letA) [Escherichia coli strain CM IVRI KOL-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482