Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SPCG_RS08305 Genome accession   NC_010582
Coordinates   1577417..1578094 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae CGSP14     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1572417..1583094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPCG_RS08280 (SPCG_1603) - 1572578..1573207 (-) 630 WP_000762100.1 NAD(P)-dependent oxidoreductase -
  SPCG_RS14215 - 1573446..1573820 (+) 375 Protein_1570 hypothetical protein -
  SPCG_RS08290 (SPCG_1605) - 1574077..1574400 (+) 324 WP_000422779.1 MazG-like protein -
  SPCG_RS08295 (SPCG_1606) thrS 1574458..1576401 (+) 1944 WP_000608356.1 threonine--tRNA ligase -
  SPCG_RS08300 (SPCG_1607) - 1576450..1577424 (-) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  SPCG_RS08305 (SPCG_1608) braR 1577417..1578094 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  SPCG_RS08310 (SPCG_1609) - 1578250..1579323 (+) 1074 WP_001273828.1 DUF2974 domain-containing protein -
  SPCG_RS08315 - 1579414..1579717 (-) 304 Protein_1576 hypothetical protein -
  SPCG_RS08320 (SPCG_1610) - 1579786..1580223 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  SPCG_RS08325 (SPCG_1611) - 1580299..1581141 (-) 843 WP_000160943.1 metallophosphoesterase -
  SPCG_RS08330 (SPCG_1612) - 1581253..1581903 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=28230 SPCG_RS08305 WP_000548959.1 1577417..1578094(-) (braR) [Streptococcus pneumoniae CGSP14]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=28230 SPCG_RS08305 WP_000548959.1 1577417..1578094(-) (braR) [Streptococcus pneumoniae CGSP14]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment