Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LL14B4_RS09495 Genome accession   NZ_CP028160
Coordinates   1943075..1943776 (-) Length   233 a.a.
NCBI ID   WP_109991145.1    Uniprot ID   A0A2Z3KR48
Organism   Lactococcus lactis subsp. lactis strain 14B4     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1938075..1948776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL14B4_RS09475 (LL14B4_09465) - 1938186..1939403 (-) 1218 WP_109991144.1 cysteine desulfurase -
  LL14B4_RS09480 (LL14B4_09470) sufD 1939403..1940659 (-) 1257 WP_017864923.1 Fe-S cluster assembly protein SufD -
  LL14B4_RS09485 (LL14B4_09475) sufC 1940796..1941566 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  LL14B4_RS09490 (LL14B4_09480) - 1941741..1943072 (-) 1332 WP_021722251.1 glycosyltransferase family 4 protein -
  LL14B4_RS09495 (LL14B4_09485) mecA 1943075..1943776 (-) 702 WP_109991145.1 adaptor protein MecA Regulator
  LL14B4_RS09500 (LL14B4_09490) - 1943906..1944640 (-) 735 WP_004255171.1 amino acid ABC transporter ATP-binding protein -
  LL14B4_RS09505 (LL14B4_09495) - 1944640..1945326 (-) 687 WP_033899921.1 amino acid ABC transporter permease -
  LL14B4_RS09510 (LL14B4_09500) - 1945474..1946382 (-) 909 WP_033899919.1 diacylglycerol/lipid kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27105.51 Da        Isoelectric Point: 4.1246

>NTDB_id=281819 LL14B4_RS09495 WP_109991145.1 1943075..1943776(-) (mecA) [Lactococcus lactis subsp. lactis strain 14B4]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEVTKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=281819 LL14B4_RS09495 WP_109991145.1 1943075..1943776(-) (mecA) [Lactococcus lactis subsp. lactis strain 14B4]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGTAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z3KR48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.142

100

0.991
  mecA Lactococcus lactis subsp. cremoris KW2

96.567

100

0.966

Multiple sequence alignment